{"id":"W2007488022","doi":"10.1007/s12672-010-0013-y","title":"Circulating Insulin-like Growth Factor (IGF)-I and IGF Binding Protein (IGFBP)-3 Levels and Postmenopausal Breast Cancer Risk in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial (PLCO) Cohort","year":2010,"lang":"en","type":"article","venue":"Hormones and Cancer","topic":"Growth Hormone and Insulin-like Growth Factors","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Jewish General Hospital","funders":"National Cancer Institute; National Institutes of Health; Division of Cancer Prevention, National Cancer Institute; U.S. Department of Health and Human Services","keywords":"Medicine; Hazard ratio; Breast cancer; Internal medicine; Oncology; Proportional hazards model; Prospective cohort study; Insulin-like growth factor; Risk factor; Cancer; Prostate cancer; Gynecology; Endocrinology; Confidence interval; Growth factor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006348992,0.0005621549,0.0007670473,0.0002471624,0.0005819415,0.0002568831,0.0001329353,0.0003425857,0.00007840707],"category_scores_gemma":[0.0001060603,0.0004020134,0.00006023322,0.0004574368,0.0003773452,0.0004885495,0.0001546835,0.001074379,5.964302e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00010694,"about_ca_system_score_gemma":0.0003140704,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01712318,"about_ca_topic_score_gemma":0.002358788,"domain_scores_codex":[0.9971252,0.000142349,0.0006448448,0.0008711676,0.0004858791,0.0007305435],"domain_scores_gemma":[0.9986961,0.0001575905,0.0003513352,0.0002508325,0.0001797226,0.0003643522],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.007366597,0.0001115592,0.8789157,0.0002659379,0.0003094122,0.00006269864,0.00396762,0.000001064586,0.07807234,0.00008375676,0.0001656505,0.03067771],"study_design_scores_gemma":[0.01736341,0.0005924034,0.9779074,0.0002974745,0.0003691031,0.0001829248,0.00064985,0.0005671924,0.001089613,0.00006342828,0.0003589046,0.000558316],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9850432,0.009461253,0.0000104893,0.001149042,0.0003448172,0.00310449,0.0007277491,0.00006000302,0.00009890675],"genre_scores_gemma":[0.9915032,0.00633803,0.0001633874,0.0003163911,0.0005597506,0.0009336006,0.00002597202,0.00007748934,0.00008215909],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09899174,"threshold_uncertainty_score":0.9998432,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01527267404314949,"score_gpt":0.2687764677882709,"score_spread":0.2535037937451214,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}