{"id":"W2007563650","doi":"10.1371/journal.pone.0076642","title":"The CpG Island in the Murine Foxl2 Proximal Promoter Is Differentially Methylated in Primary and Immortalized Cells","year":2013,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; McGill University","keywords":"CpG site; Biology; DNA methylation; Methylation; Molecular biology; Cell biology; Genetics; HEK 293 cells; Cell culture; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000137207,0.0002575621,0.0002008095,0.000237667,0.0001330729,0.0001856142,0.0001559296,0.0001711376,0.001394155],"category_scores_gemma":[0.0001273461,0.0002214149,0.0003052741,0.0001494186,0.0002137636,0.00008863946,0.0002087555,0.0004446791,0.0007673107],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002695344,"about_ca_system_score_gemma":0.0002588271,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001000608,"about_ca_topic_score_gemma":0.001412515,"domain_scores_codex":[0.9998167,0.00001692337,0.0000121796,0.00007198675,0.00004515263,0.00003710355],"domain_scores_gemma":[0.999905,0.00001531361,0.00002310348,0.00001786382,0.00001254156,0.00002623771],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002528534,0.000004191321,0.00009652706,0.00001038927,0.00000213546,0.00001545442,0.000008710706,0.00001343963,0.9993587,0.00003373474,0.0000121103,0.0004193432],"study_design_scores_gemma":[0.00001037287,0.0001113308,0.006126036,0.000006896451,0.00001747068,0.0002182239,0.00001416279,0.0006238702,0.9885324,0.00005419112,0.004281322,0.000003753367],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9710575,0.002839109,0.02089811,0.0001375428,0.00008332725,0.00006617307,0.00191535,0.0003004426,0.002702486],"genre_scores_gemma":[0.9742301,0.001301587,0.009609089,0.0001114776,0.00002419667,0.0001270169,0.005002815,0.00009825977,0.009495532],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001394155,"threshold_uncertainty_score":0.004663885,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01416436753642296,"score_gpt":0.2116905005502529,"score_spread":0.1975261330138299,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}