{"id":"W2007626080","doi":"10.1186/1742-4690-6-s3-p67","title":"P04-39. Recognizing a dynamic HIV-1 target: a structural look at the interaction between bnAb 2F5 and varying gp41 MPER sequences","year":2009,"lang":"en","type":"article","venue":"Retrovirology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Human immunodeficiency virus (HIV); Computer science; Medicine; Computational biology; Virology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00020668,0.0002046046,0.0003019513,0.0001178568,0.0004852795,0.00002522945,0.0001725778,0.0002530231,0.000778577],"category_scores_gemma":[0.00007918471,0.0001337257,0.00007686934,0.00009432786,0.0003624462,0.0001308864,0.0001104538,0.0005062831,0.0009323702],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001711634,"about_ca_system_score_gemma":0.00004343754,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001143219,"about_ca_topic_score_gemma":0.00006096816,"domain_scores_codex":[0.9983619,0.0003877585,0.0002383619,0.0004048558,0.00004606983,0.0005609849],"domain_scores_gemma":[0.999275,0.000308658,0.0001026784,0.0002379148,0.00003131055,0.00004445128],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001101136,0.00007458415,0.2208677,0.00002659993,0.0009506947,0.0001258656,0.001883094,0.00003147235,0.6354673,0.0001502774,0.001731418,0.1375899],"study_design_scores_gemma":[0.009741433,0.007161292,0.8323027,0.0001133614,0.0005603927,0.003550536,0.001319259,0.0004610393,0.07068665,0.005878279,0.06688198,0.001343058],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.991978,0.003325161,0.00005358703,0.003266449,0.0002105862,0.0002630794,0.00008577744,0.00005414897,0.0007631903],"genre_scores_gemma":[0.9968662,0.0001843795,0.0001110426,0.0002948882,0.00005205971,0.00001702735,0.0004141529,0.00001151242,0.002048752],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.611435,"threshold_uncertainty_score":0.9998455,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01490359419697642,"score_gpt":0.2784615029017598,"score_spread":0.2635579087047834,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}