{"id":"W2007683452","doi":"10.1139/v00-155","title":"Synthesis of 5-fluoro-β-<scp>D</scp>-glucopyranosyluronic acid fluoride and its evaluation as a mechanistic probe of <i>Escherichia coli </i>β-glucuronidase","year":2001,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Networks of Centres of Excellence of Canada; Natural Sciences and Engineering Research Council of Canada; Medical Research Council Canada","keywords":"Chemistry; Electrospray ionization; Fluoride; Nucleophile; Tandem mass spectrometry; Mass spectrometry; Combinatorial chemistry; Stereochemistry; Organic chemistry; Chromatography; Catalysis; Inorganic chemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002468235,0.0004931392,0.0002233597,0.0001281604,0.0001575899,0.0002161461,0.0003316619,0.0004668905,0.0006152246],"category_scores_gemma":[0.0001782917,0.0001408969,0.0002307988,0.0001590251,0.0002057428,0.0001711772,0.0001422235,0.0004225232,0.0003188982],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00033029,"about_ca_system_score_gemma":0.0002534646,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001098368,"about_ca_topic_score_gemma":0.0007088918,"domain_scores_codex":[0.9998541,0.00002946211,0.000008611913,0.00004134479,0.00003028359,0.00003620022],"domain_scores_gemma":[0.9998822,0.00001828467,0.00003172143,0.00001646598,0.00002746654,0.00002385488],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003913758,0.000009324792,0.00004427308,0.00002230949,0.000002716626,0.00003197979,0.000009069154,0.00007646697,0.9988281,0.00008216322,0.00001656951,0.000837796],"study_design_scores_gemma":[0.000003803036,0.000124213,0.0002129232,0.000001413647,0.000003379765,0.00005606194,0.000003755429,0.000156836,0.9986635,0.00001156813,0.000760134,0.000002378874],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9714714,0.001186974,0.02378666,0.0001027959,0.00003060301,0.0001047178,0.0005259828,0.0001103931,0.002680543],"genre_scores_gemma":[0.9790638,0.0007397884,0.01732489,0.00007430643,0.000008393897,0.00006155356,0.0006710035,0.00002876452,0.002027418],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001098368,"threshold_uncertainty_score":0.002396405,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01241630763165561,"score_gpt":0.250597429364477,"score_spread":0.2381811217328214,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}