{"id":"W2007916618","doi":"10.1016/j.devcel.2010.03.007","title":"The Hippo Pathway Regulates Wnt/β-Catenin Signaling","year":2010,"lang":"en","type":"article","venue":"Developmental Cell","topic":"Hippo pathway signaling and YAP/TAZ","field":"Biochemistry, Genetics and Molecular Biology","cited_by":566,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"Canadian Cancer Society Research Institute; Canadian Institutes of Health Research; Canadian Cancer Society; Howard Hughes Medical Institute","keywords":"Wnt signaling pathway; Hippo signaling pathway; Biology; Cell biology; Signal transduction; Beta-catenin; Phosphorylation; Catenin; Cytoplasm; Signal transducing adaptor protein","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009101912,0.0004325234,0.0001699795,0.0004967916,0.0004808689,0.0006237053,0.0002223434,0.000275381,0.001078598],"category_scores_gemma":[0.0001099562,0.0002331752,0.0001555902,0.0002500475,0.0004215783,0.0006193757,0.0003416461,0.0005880976,0.0003760079],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001023495,"about_ca_system_score_gemma":0.0004423952,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002192263,"about_ca_topic_score_gemma":0.004139535,"domain_scores_codex":[0.9999241,0.000005855764,0.000003218262,0.00001272095,0.00002319404,0.00003088151],"domain_scores_gemma":[0.9999467,0.000003584298,0.00001830322,0.000003075414,0.000009648806,0.00001866181],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001917904,0.00001188797,0.0007476188,0.00005936121,0.000009228158,0.0002346313,0.00003101737,0.0001806237,0.9914454,0.003167198,0.0003101487,0.003611067],"study_design_scores_gemma":[0.00003119325,0.00005957497,0.02062161,0.0000159655,0.00002754031,0.0004124713,0.0001113582,0.002152678,0.9620614,0.001108486,0.01338325,0.00001444213],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9571236,0.01775493,0.00824598,0.001272319,0.0001238347,0.00004947311,0.000848429,0.0003022347,0.01427931],"genre_scores_gemma":[0.9831812,0.005892584,0.001589744,0.00008439778,0.00003860737,0.00001895305,0.0004465047,0.00003903022,0.008709101],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002192263,"threshold_uncertainty_score":0.007426083,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005722244108453269,"score_gpt":0.1924757942077066,"score_spread":0.1867535500992533,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}