{"id":"W2007949372","doi":"10.1093/humrep/dev079","title":"Preimplantation genetic screening using comprehensive chromosome screening: evidence and remaining challenges","year":2015,"lang":"en","type":"letter","venue":"Human Reproduction","topic":"Prenatal Screening and Diagnostics","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"","keywords":"Genetics; Biology; Medicine; Computational biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01093652,0.0004880888,0.001262367,0.001276622,0.001503573,0.002912102,0.00188667,0.01791026,0.003864902],"category_scores_gemma":[0.06807002,0.0003982719,0.0007139869,0.0009868479,0.003750784,0.005076787,0.001635552,0.01772224,0.001562758],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002320401,"about_ca_system_score_gemma":0.003319524,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003040887,"about_ca_topic_score_gemma":0.005558827,"domain_scores_codex":[0.9936209,0.003129756,0.001057159,0.0005283498,0.001343921,0.0003198436],"domain_scores_gemma":[0.9070579,0.07893512,0.00351923,0.001265294,0.00680868,0.002413856],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002891073,0.0001532468,0.02282685,0.001803122,0.0001585806,0.02995092,0.0007662163,0.000386176,0.0007767872,0.03197099,0.7194238,0.1914941],"study_design_scores_gemma":[0.0002311644,0.0002703977,0.01004874,0.01096439,0.0003805002,0.0750305,0.003508585,0.001268524,0.0007740227,0.09596312,0.8013941,0.0001660076],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0007773039,0.0223197,0.0002630631,0.9705957,0.004026812,0.00000332925,0.00004442133,0.00001056395,0.001959138],"genre_scores_gemma":[0.03403863,0.08227388,0.002555195,0.7803032,0.09857777,0.00002791207,0.0001349857,0.00002725431,0.002061126],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.01791026,"threshold_uncertainty_score":0.05783856,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2873193349241969,"score_gpt":0.3639550063693455,"score_spread":0.0766356714451486,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}