{"id":"W2007979842","doi":"10.1038/onc.2014.396","title":"Hypoxic regulation of RIOK3 is a major mechanism for cancer cell invasion and metastasis","year":2014,"lang":"en","type":"article","venue":"Oncogene","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":53,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"BC Cancer Agency; European Commission; National Institute for Health and Care Research; Cancer Research UK; Breast Cancer Research Foundation","keywords":"Biology; Cell migration; Actin; Metastasis; Cell biology; Cytoskeleton; Actin cytoskeleton; Invadopodia; Cancer cell; Cell; Cancer research; Cancer; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000135215,0.000381718,0.000266454,0.0002479713,0.0004743736,0.0004542828,0.0003527004,0.0002766504,0.003282387],"category_scores_gemma":[0.0001329836,0.0001663139,0.0004563605,0.0002088881,0.0002970505,0.0003275961,0.0004576622,0.0006214079,0.0007576935],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007240305,"about_ca_system_score_gemma":0.0003654686,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007600587,"about_ca_topic_score_gemma":0.001402371,"domain_scores_codex":[0.99986,0.00001087619,0.000006810221,0.00003414684,0.00003474546,0.00005327198],"domain_scores_gemma":[0.9999177,0.000005368744,0.00002808882,0.00001029496,0.000009818814,0.0000287159],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004334037,0.00005947949,0.001685018,0.0001384207,0.000029638,0.0002864922,0.00003315811,0.0001703093,0.9900226,0.001647756,0.0007896434,0.004704185],"study_design_scores_gemma":[0.00005081826,0.0002537896,0.05362093,0.00001830796,0.00006234987,0.001278463,0.0001390589,0.001761887,0.9234123,0.001149472,0.01823054,0.00002210134],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9667895,0.009065578,0.007155582,0.000894354,0.000164468,0.00007261219,0.001800454,0.0004684623,0.01358907],"genre_scores_gemma":[0.9925684,0.001327131,0.001018169,0.0001268517,0.00002426897,0.00004289894,0.0009665103,0.0000344656,0.00389143],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003282387,"threshold_uncertainty_score":0.01098073,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01778623874559349,"score_gpt":0.2518599558219267,"score_spread":0.2340737170763332,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}