{"id":"W2008002238","doi":"10.3389/fncel.2014.00125","title":"Ligand-gated ion channel interacting proteins and their role in neuroprotection","year":2014,"lang":"en","type":"review","venue":"Frontiers in Cellular Neuroscience","topic":"Nicotinic Acetylcholine Receptors Study","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre for Addiction and Mental Health","funders":"","keywords":"Ionotropic effect; Ion channel; Neuroprotection; Ion channel linked receptors; Neuroscience; Ligand-gated ion channel; Receptor; Neurotransmitter receptor; Chemistry; Excitotoxicity; Biology; TRPC1; Cell biology; Glutamate receptor; AMPA receptor; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000257167,0.0006048241,0.0009037597,0.00144485,0.0002465947,0.000687981,0.0006134856,0.0008044944,0.002761906],"category_scores_gemma":[0.0002220574,0.0001800443,0.0002893098,0.001770261,0.0003719312,0.000906178,0.0004916987,0.0009580115,0.00224088],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005099808,"about_ca_system_score_gemma":0.0005973046,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000489742,"about_ca_topic_score_gemma":0.0007594039,"domain_scores_codex":[0.9999126,0.00001229284,0.00001204046,0.00001673589,0.00003386222,0.00001242482],"domain_scores_gemma":[0.9999292,0.000021681,0.00001215265,0.000002605049,0.00002345852,0.00001086706],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008945158,0.00006432034,0.0001709759,0.01253648,0.00006449227,0.0003957065,0.0000997328,0.000367321,0.01187855,0.008543642,0.0185109,0.9472783],"study_design_scores_gemma":[0.0000103575,0.0000732117,0.000708643,0.001149338,0.00005460884,0.001186067,0.00006180631,0.00007354151,0.002224104,0.002991986,0.9914504,0.0000159308],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002393158,0.9978366,0.0002094942,0.0001511427,0.0001268339,0.000003974098,0.00001793956,0.000009346271,0.00140543],"genre_scores_gemma":[0.001412792,0.9970627,0.0002458482,0.00009563607,0.00009301882,0.000006952654,0.00002971575,0.00000162243,0.001051747],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002761906,"threshold_uncertainty_score":0.009239495,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01550238450921032,"score_gpt":0.262840883258811,"score_spread":0.2473384987496007,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}