{"id":"W2008041925","doi":"10.1128/jvi.01644-08","title":"DNA Genome Size Affects the Stability of the Adenovirus Virion","year":2008,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa; Health Canada","funders":"Canadian Institutes of Health Research; Muscular Dystrophy Canada; ALS Society of Canada","keywords":"Biology; Genome; Capsid; Genome size; Adenovirus genome; DNA; Viral replication; Genetics; Infectivity; Virus; ENCODE; Virology; Adenoviridae; Gene; Recombinant DNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000891281,0.0001085311,0.000210124,0.00002989979,0.0001234633,0.000004209558,0.0006102711,0.0001442816,0.0001042781],"category_scores_gemma":[0.000344832,0.0000591351,0.0002199638,0.0001132703,0.0005500218,0.000003790804,0.000148609,0.0003061987,0.000004355409],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002424473,"about_ca_system_score_gemma":0.0002508732,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004740511,"about_ca_topic_score_gemma":0.00005058941,"domain_scores_codex":[0.9984909,0.0005756844,0.0003060008,0.0001362702,0.0002653433,0.0002258106],"domain_scores_gemma":[0.9988602,0.000123938,0.0003235193,0.0004806872,0.0001523699,0.00005928193],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002032933,0.00009367716,0.003290101,0.000006050215,0.00008626493,0.000008464838,0.0001109926,0.00009379547,0.9936792,0.000004694753,0.0003003017,0.0002935651],"study_design_scores_gemma":[0.0008051066,0.004406862,0.08001325,0.000003267587,0.00002110742,0.0003363561,0.00003488208,0.000005596058,0.9083444,0.00009389698,0.005864828,0.00007038504],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959992,0.00191137,0.00004395778,0.001564557,0.0001699504,0.0001504832,0.000006799215,0.00000148411,0.0001522293],"genre_scores_gemma":[0.9983829,0.0005899768,0.00003274513,0.0006238429,0.000279181,0.000002835352,8.009004e-7,0.00001355386,0.00007419468],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0853347,"threshold_uncertainty_score":0.241146,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02008021344958027,"score_gpt":0.2774385721328564,"score_spread":0.2573583586832761,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}