{"id":"W2008041925","doi":"10.1128/jvi.01644-08","title":"DNA Genome Size Affects the Stability of the Adenovirus Virion","year":2008,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa; Health Canada","funders":"Canadian Institutes of Health Research; Muscular Dystrophy Canada; ALS Society of Canada","keywords":"Biology; Genome; Capsid; Genome size; Adenovirus genome; DNA; Viral replication; Genetics; Infectivity; Virus; ENCODE; Virology; Adenoviridae; Gene; Recombinant DNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000505552,0.0002400455,0.0001874781,0.0003440483,0.0001349955,0.0006203768,0.000209485,0.0003176287,0.001496551],"category_scores_gemma":[0.001473653,0.0002512213,0.0002075215,0.0001471154,0.0002446969,0.0004635171,0.000260422,0.0004333298,0.0003870455],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003119698,"about_ca_system_score_gemma":0.0001834535,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003487927,"about_ca_topic_score_gemma":0.0002995361,"domain_scores_codex":[0.9997115,0.00006222913,0.00003491697,0.00006742126,0.00008608324,0.00003786953],"domain_scores_gemma":[0.998871,0.0005701771,0.0001796536,0.00006925644,0.0001833071,0.0001265345],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008023612,0.0000112923,0.0004020798,0.00001986711,0.000005760672,0.0000161274,0.00002776318,0.00005292911,0.998216,0.00007145924,0.00001802836,0.001078483],"study_design_scores_gemma":[0.00001011977,0.0003842654,0.009797897,0.00000950592,0.00003181172,0.0002356343,0.00003549649,0.0006358208,0.9874424,0.0001171573,0.001287482,0.00001235761],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949786,0.001809588,0.001802317,0.00007047363,0.00003344407,0.0000114499,0.0001384886,0.00003935942,0.001116192],"genre_scores_gemma":[0.9968711,0.0007118054,0.001061455,0.00003629968,0.0000138273,0.00001565775,0.0002997693,0.00003317967,0.0009569768],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001496551,"threshold_uncertainty_score":0.005006492,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02008021344958027,"score_gpt":0.2774385721328564,"score_spread":0.2573583586832761,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}