{"id":"W2008085142","doi":"10.1021/bi6023786","title":"Structural and Functional Analysis of ProQ:  An Osmoregulatory Protein of <i>Escherichia coli</i>","year":2007,"lang":"en","type":"article","venue":"Biochemistry","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"National Institute of Allergy and Infectious Diseases; University of Colorado Denver","keywords":"Circular dichroism; Escherichia coli; Chemistry; C-terminus; Biochemistry; Thermostability; Linker; Stereochemistry; Biophysics; Amino acid; Crystallography; Biology; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001617881,0.0001275321,0.0002046235,0.00006132024,0.00002727383,0.000005113401,0.0001142043,0.0003210493,0.00002082025],"category_scores_gemma":[0.00002445281,0.0001213479,0.00008359228,0.0002297016,0.0002684518,0.000001974468,0.00008413536,0.00006210486,1.028138e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006376229,"about_ca_system_score_gemma":0.00006051235,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001428618,"about_ca_topic_score_gemma":0.00001585288,"domain_scores_codex":[0.9991603,0.00001218267,0.0002696012,0.0002922862,0.0001071884,0.0001584686],"domain_scores_gemma":[0.999323,0.000003505624,0.0001637107,0.0003266031,0.0001119167,0.0000712808],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001751576,0.00003969002,0.004822833,0.00004223912,0.0002433051,4.988111e-7,0.00000782096,0.000005877047,0.9937702,0.00005863282,0.00002115766,0.0008126327],"study_design_scores_gemma":[0.0002357169,0.0001605984,0.06714618,0.000005022829,0.0001175486,0.000002610479,0.00003981361,0.00004972565,0.9318379,0.00002076029,0.0002605881,0.000123496],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991854,0.0003436139,0.0001391171,0.00001844565,0.00003788912,0.000103332,0.00005767337,0.000007144716,0.0001074299],"genre_scores_gemma":[0.9982511,0.00001000231,0.001278852,0.0000236336,0.00009077321,0.000004019317,0.000217295,0.000009996813,0.0001143698],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06232335,"threshold_uncertainty_score":0.4948425,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00686460839048696,"score_gpt":0.217665200728418,"score_spread":0.210800592337931,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}