{"id":"W2008085142","doi":"10.1021/bi6023786","title":"Structural and Functional Analysis of ProQ:  An Osmoregulatory Protein of <i>Escherichia coli</i>","year":2007,"lang":"en","type":"article","venue":"Biochemistry","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"National Institute of Allergy and Infectious Diseases; University of Colorado Denver","keywords":"Circular dichroism; Escherichia coli; Chemistry; C-terminus; Biochemistry; Thermostability; Linker; Stereochemistry; Biophysics; Amino acid; Crystallography; Biology; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001162073,0.0003209127,0.0001443944,0.0001267387,0.0001363545,0.0001971922,0.0002133997,0.0002400752,0.0003906003],"category_scores_gemma":[0.0001523784,0.0000830397,0.0002232975,0.0001789046,0.0001994045,0.0001751066,0.0001236458,0.0003187499,0.0002600719],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003158989,"about_ca_system_score_gemma":0.0001790985,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001049016,"about_ca_topic_score_gemma":0.0007143691,"domain_scores_codex":[0.9999316,0.00001387629,0.000006063308,0.00001537747,0.00002220497,0.00001097474],"domain_scores_gemma":[0.9998901,0.00001918231,0.00003196126,0.000008235776,0.0000263585,0.00002414406],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008844343,0.00002463224,0.0003958237,0.00003019033,0.00000356185,0.00007488058,0.00001402324,0.0001276504,0.9986474,0.00004014962,0.00002327288,0.0005299955],"study_design_scores_gemma":[0.00001768515,0.000334637,0.02818173,0.00001065316,0.0000245867,0.001079259,0.00008494397,0.003353736,0.9637595,0.0000631962,0.003078216,0.00001190362],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973601,0.0004184806,0.001272948,0.00007337285,0.000005845731,0.00001596176,0.0005289389,0.00001609438,0.0003082717],"genre_scores_gemma":[0.9908252,0.0005059222,0.004312372,0.0000889141,0.000007981675,0.00002262554,0.003287528,0.00002747064,0.0009219305],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001049016,"threshold_uncertainty_score":0.002292037,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00686460839048696,"score_gpt":0.217665200728418,"score_spread":0.210800592337931,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}