{"id":"W2008087702","doi":"10.2174/156720505774330573","title":"The Role of Apoptotic Pathways in Alzheimers Disease Neurodegeneration and Cell Death","year":2005,"lang":"en","type":"review","venue":"Current Alzheimer Research","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":112,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Institute of Neurological Disorders and Stroke","keywords":"Neurodegeneration; Neuroscience; Alzheimer's disease; Mechanism (biology); Disease; Programmed cell death; Dementia; Frontotemporal dementia; Biology; Effector; Apoptosis; Medicine; Cell biology; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001328231,0.0005920275,0.001296511,0.0008351555,0.0003822425,0.000125066,0.0004791021,0.0001984167,0.00006017828],"category_scores_gemma":[0.0002224131,0.0003871515,0.0004778779,0.0009442981,0.0005370766,0.0001500508,0.0004331755,0.001594492,0.0001774346],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001599738,"about_ca_system_score_gemma":0.00234517,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004240135,"about_ca_topic_score_gemma":0.00001168328,"domain_scores_codex":[0.9939196,0.001203426,0.0009415339,0.0009529983,0.001753613,0.001228801],"domain_scores_gemma":[0.9963506,0.0008243942,0.0002304143,0.001077083,0.0003736578,0.001143838],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001857303,0.0009521484,0.0006241404,0.002246623,0.002681686,0.0000630518,0.00004777408,7.085565e-7,0.000001429462,0.0005720073,0.0002629849,0.9923617],"study_design_scores_gemma":[0.001665315,0.0004358715,0.000702853,0.006830987,0.008900806,0.00002129455,0.00008469792,0.0004121265,0.00008518375,0.0004105005,0.9798878,0.0005625414],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0007513846,0.9946065,4.221425e-7,0.00006715859,0.0001164431,0.003665913,0.0001497195,0.00002810432,0.000614383],"genre_scores_gemma":[0.01821346,0.9797547,0.00002896103,0.00000361455,0.0003101715,0.001110627,0.0004467256,0.0001128894,0.00001882275],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9917992,"threshold_uncertainty_score":0.999858,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2335468839490478,"score_gpt":0.447775750704174,"score_spread":0.2142288667551262,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}