{"id":"W2008155596","doi":"10.1021/bi700200z","title":"Domain Stability and Metal-Induced Folding of Calcium- and Integrin-Binding Protein 1","year":2007,"lang":"en","type":"article","venue":"Biochemistry","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Chemistry; EF hand; Calmodulin; Calcium-binding protein; Biophysics; Protein folding; Intrinsically disordered proteins; Nuclear magnetic resonance spectroscopy; Folding (DSP implementation); Crystallography; Protein structure; Calcium; Biochemistry; Stereochemistry; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007584462,0.0001100781,0.000213602,0.00005653445,0.00003725638,0.00000933635,0.00005336349,0.0001253527,0.00007373745],"category_scores_gemma":[0.0002954143,0.00009600761,0.00004125515,0.0001388088,0.0001349041,0.00001911114,0.0001250179,0.0002225287,0.000001172336],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007368054,"about_ca_system_score_gemma":0.00007198186,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003053209,"about_ca_topic_score_gemma":0.000001613412,"domain_scores_codex":[0.9989815,0.00001813085,0.0002301562,0.0002778877,0.000265569,0.0002267825],"domain_scores_gemma":[0.9993473,0.00007549157,0.00005655704,0.000242534,0.00007544056,0.0002026344],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001358717,0.00005470102,0.00554311,0.0005194321,0.00002219151,0.00003052233,0.00007857609,2.125788e-9,0.9915048,0.00002833078,0.00000801573,0.002074431],"study_design_scores_gemma":[0.0006292355,0.00008192538,0.002522875,0.0001203947,0.00001598262,0.00004038997,0.0007256732,0.000005702061,0.9956593,0.00002821491,0.00008819827,0.00008210721],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974497,0.0002596865,0.0001543197,0.000103517,0.000009761821,0.000291119,0.000003364606,0.00001714864,0.001711361],"genre_scores_gemma":[0.9968677,0.000005647737,0.002719101,0.000008440863,0.00003386301,0.000006574595,0.000005015323,0.00001251808,0.0003411721],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004154485,"threshold_uncertainty_score":0.3915077,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04186022630167612,"score_gpt":0.3261777117934084,"score_spread":0.2843174854917323,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}