{"id":"W2008163704","doi":"10.1016/j.jmb.2009.06.074","title":"Structural Insights into Antibody Recognition of Mycobacterial Polysaccharides","year":2009,"lang":"en","type":"article","venue":"Journal of Molecular Biology","topic":"Mycobacterium research and diagnosis","field":"Medicine","cited_by":49,"is_retracted":false,"has_abstract":false,"ca_institutions":"Alberta Glycomics Centre; University of Alberta; University of Calgary","funders":"National Center for Research Resources; National Institute of General Medical Sciences; Canadian Institutes of Health Research; National Institutes of Health; National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; Alberta Heritage Foundation for Medical Research; Alberta Ingenuity; Colorado State University; U.S. Department of Energy","keywords":"Lipoarabinomannan; Epitope; Antibody; Complementarity determining region; Computational biology; Biology; Chemistry; Antigen; Mycobacterium tuberculosis; Tuberculosis; Genetics; Monoclonal antibody; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001917272,0.0002759184,0.0001405988,0.0001313137,0.0001552205,0.0002630843,0.0002943972,0.0003188006,0.001239875],"category_scores_gemma":[0.0001678893,0.0001543725,0.0002328484,0.0000938442,0.0002420883,0.0003996514,0.0001699926,0.0008011032,0.0003810272],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002537271,"about_ca_system_score_gemma":0.0002108041,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005553955,"about_ca_topic_score_gemma":0.000596898,"domain_scores_codex":[0.9999532,0.00001006168,0.000002039847,0.000005308727,0.00001222158,0.00001714698],"domain_scores_gemma":[0.9999344,0.0000248489,0.000009649156,0.000005217048,0.00001059903,0.00001521736],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002181167,0.0001105731,0.0006885043,0.0001413015,0.00001392533,0.0006230778,0.0001221781,0.001558516,0.9814364,0.00555487,0.0002360668,0.009296466],"study_design_scores_gemma":[0.0000720737,0.0008726513,0.005630943,0.00003840262,0.00005114633,0.00156137,0.0002993863,0.01419625,0.9574641,0.006290524,0.01350256,0.00002063782],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.972999,0.004875922,0.01504735,0.0009630989,0.0001025917,0.000024013,0.00007862447,0.0000504456,0.005859063],"genre_scores_gemma":[0.9905367,0.002396314,0.005011279,0.0002474489,0.00002723614,0.000005057986,0.0001316198,0.000005404745,0.00163888],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001239875,"threshold_uncertainty_score":0.004147768,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01706848160132213,"score_gpt":0.3370963461140183,"score_spread":0.3200278645126962,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}