{"id":"W2008163704","doi":"10.1016/j.jmb.2009.06.074","title":"Structural Insights into Antibody Recognition of Mycobacterial Polysaccharides","year":2009,"lang":"en","type":"article","venue":"Journal of Molecular Biology","topic":"Mycobacterium research and diagnosis","field":"Medicine","cited_by":49,"is_retracted":false,"has_abstract":false,"ca_institutions":"Alberta Glycomics Centre; University of Alberta; University of Calgary","funders":"National Center for Research Resources; National Institute of General Medical Sciences; Canadian Institutes of Health Research; National Institutes of Health; National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; Alberta Heritage Foundation for Medical Research; Alberta Ingenuity; Colorado State University; U.S. Department of Energy","keywords":"Lipoarabinomannan; Epitope; Antibody; Complementarity determining region; Computational biology; Biology; Chemistry; Antigen; Mycobacterium tuberculosis; Tuberculosis; Genetics; Monoclonal antibody; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001651636,0.0001020797,0.0003873591,0.0002698739,0.00002271097,0.00000892459,0.0001037148,0.0001287969,0.00006996271],"category_scores_gemma":[0.0004566112,0.00007196513,0.0001747063,0.0001317363,0.00007120926,0.00007462115,0.00001974229,0.0001998075,0.000006371451],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003030904,"about_ca_system_score_gemma":0.0001361124,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002336803,"about_ca_topic_score_gemma":0.000001283833,"domain_scores_codex":[0.998989,0.0001197771,0.0004456356,0.0001054833,0.000167395,0.0001726701],"domain_scores_gemma":[0.9989944,0.00004857337,0.0002955538,0.0001221692,0.0003766748,0.0001626754],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008986429,0.00006826759,0.006022952,0.00002189524,0.00008401382,0.0001758731,0.00007609182,2.835018e-7,0.9781627,0.0001305881,0.00007230178,0.01428638],"study_design_scores_gemma":[0.001991841,0.005401714,0.1046058,0.0001359136,0.0001014234,0.0004936909,0.00002975332,0.000008371137,0.8766493,0.01014905,0.0003325203,0.0001006954],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973844,0.0009108038,0.0004104971,0.0008412738,0.0002652271,0.00009494187,0.000004283297,0.0000107216,0.00007780457],"genre_scores_gemma":[0.996711,0.000414126,0.002089799,0.000403982,0.0003390215,5.129481e-7,0.00002945055,0.00001034444,0.000001807189],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1015135,"threshold_uncertainty_score":0.2934653,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01706848160132213,"score_gpt":0.3370963461140183,"score_spread":0.3200278645126962,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}