{"id":"W2008181517","doi":"10.1007/s10495-007-0087-3","title":"The inhibitors of apoptosis (IAPs) as cancer targets","year":2007,"lang":"en","type":"review","venue":"APOPTOSIS","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":570,"is_retracted":false,"has_abstract":false,"ca_institutions":"Children's Hospital of Eastern Ontario; University of Ottawa","funders":"","keywords":"XIAP; Cancer; Cancer research; Neurodegeneration; Carcinogenesis; Inhibitor of apoptosis; Biology; Apoptosis; Cancer cell; Transcription factor; Caspase; Programmed cell death; Immunology; Disease; Medicine; Gene; Genetics; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007740628,0.001508074,0.001574859,0.001767322,0.0003801912,0.001316785,0.001304998,0.001360098,0.002364244],"category_scores_gemma":[0.0006260829,0.000463009,0.0004298321,0.002380121,0.0008114707,0.001263725,0.0007044933,0.003719525,0.002719357],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00106106,"about_ca_system_score_gemma":0.000797992,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007312797,"about_ca_topic_score_gemma":0.001305172,"domain_scores_codex":[0.9997644,0.00002865498,0.00002793929,0.00003697368,0.0001091372,0.00003288093],"domain_scores_gemma":[0.999693,0.0001148737,0.00005178974,0.00001446413,0.00009183895,0.00003394116],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001506183,0.0001020851,0.0001723039,0.004840115,0.00005955504,0.0002849937,0.00003722412,0.0009447902,0.007075434,0.00732701,0.03905896,0.9399468],"study_design_scores_gemma":[0.00005018787,0.00009359488,0.000378488,0.0005934046,0.0000711344,0.001177483,0.00002353838,0.0001384514,0.002914429,0.002356251,0.9921888,0.00001425879],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001856594,0.9967113,0.0005486429,0.0002789979,0.000451143,0.000009435828,0.00002571677,0.00001934838,0.001769882],"genre_scores_gemma":[0.001472792,0.9953927,0.0006354584,0.0003614402,0.0002837885,0.00002208921,0.00005890142,0.000003086623,0.001769745],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002364244,"threshold_uncertainty_score":0.007909179,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02452583729191287,"score_gpt":0.3301021006735766,"score_spread":0.3055762633816637,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}