{"id":"W2008195380","doi":"10.1016/s1063-4584(10)60257-9","title":"230 VALPROIC ACID SUPPRESSES INTERLEUKIN-1β-INDUCED MICROSOMAL PROSTAGLANDIN E2 SYNTHASE-1 EXPRESSION IN CHONDROCYTES","year":2010,"lang":"en","type":"article","venue":"Osteoarthritis and Cartilage","topic":"Histone Deacetylase Inhibitors Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Prostaglandin E2; Valproic Acid; Chemistry; Microsome; Interleukin 1β; Interleukin; Internal medicine; Endocrinology; Pharmacology; Medicine; Biochemistry; Biology; Enzyme; Cytokine; Neuroscience; Epilepsy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001539088,0.0005227522,0.00052248,0.0003370105,0.0003558019,0.000508549,0.0002803812,0.0003739326,0.001846407],"category_scores_gemma":[0.0002243507,0.0002939605,0.000395562,0.000251624,0.0005335802,0.0002362797,0.0002739099,0.0007879283,0.0006577828],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003375261,"about_ca_system_score_gemma":0.0006987632,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002221343,"about_ca_topic_score_gemma":0.002631072,"domain_scores_codex":[0.9997538,0.00004738779,0.00003955028,0.00003111065,0.00004641099,0.00008177044],"domain_scores_gemma":[0.999823,0.00002814428,0.00003897692,0.00002109663,0.00002031558,0.00006853383],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.006082025,0.000198293,0.0003661074,0.00009119549,0.00003009202,0.0001682433,0.0000394119,0.00007735941,0.9904789,0.00009583592,0.0001491288,0.002223519],"study_design_scores_gemma":[0.0004960516,0.003076645,0.004626706,0.00001153527,0.00006198153,0.000430913,0.0001517835,0.000565904,0.9881074,0.0001038777,0.002352925,0.00001433689],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955714,0.002179923,0.0005800609,0.0002013831,0.0001035082,0.00001998093,0.00039924,0.0000875883,0.0008568233],"genre_scores_gemma":[0.9949107,0.001046999,0.0005765477,0.0001081454,0.00003777479,0.00003118789,0.0006199799,0.00001865298,0.002650037],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002221343,"threshold_uncertainty_score":0.006176829,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006419204405751235,"score_gpt":0.2433973384290877,"score_spread":0.2369781340233365,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}