{"id":"W2008195801","doi":"10.1053/gast.2002.36002","title":"Intestinal infection with Giardia spp. reduces epithelial barrier function in a myosin light chain kinase–dependent fashion","year":2002,"lang":"en","type":"article","venue":"Gastroenterology","topic":"Parasitic Infections and Diagnostics","field":"Immunology and Microbiology","cited_by":204,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Myosin light-chain kinase; Barrier function; Tight junction; Biology; Giardia; Cell biology; Myosin; Intestinal mucosa; Actin; Motility; Intestinal permeability; Microbiology; Immunology; Internal medicine; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001582986,0.0003311353,0.000308026,0.0001830905,0.0001347722,0.0003155704,0.0001909646,0.0003817178,0.001562342],"category_scores_gemma":[0.0002328626,0.000167589,0.0002500156,0.00009162959,0.0003111811,0.0001769826,0.0002312999,0.0006945893,0.0003298321],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002676762,"about_ca_system_score_gemma":0.0002230998,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000731518,"about_ca_topic_score_gemma":0.001234798,"domain_scores_codex":[0.9997435,0.00006063298,0.00001000998,0.00002797363,0.00005098238,0.0001068906],"domain_scores_gemma":[0.9997665,0.00003481847,0.00005586087,0.00002687572,0.00003419057,0.00008166878],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002836208,0.00006006707,0.0003340965,0.00004279103,0.00001066939,0.00003005942,0.000007605048,0.0000222788,0.9975322,0.00002837803,0.0001270161,0.001521063],"study_design_scores_gemma":[0.0001008847,0.003269388,0.1004815,0.00003559611,0.00007480499,0.0005452894,0.0001340514,0.001083327,0.8903432,0.0001529696,0.003765272,0.00001360532],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946389,0.00232915,0.0007978701,0.0002575992,0.00005408375,0.00001371118,0.00007969845,0.00009368651,0.001735375],"genre_scores_gemma":[0.9954672,0.001322222,0.0004899498,0.0001281576,0.0000179698,0.0000177352,0.0001814389,0.00001984561,0.002355509],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001562342,"threshold_uncertainty_score":0.005226493,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00835872959147297,"score_gpt":0.2067131856410397,"score_spread":0.1983544560495667,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}