{"id":"W2008221238","doi":"10.1016/j.hrthm.2006.04.016","title":"Genetic determinants of atrial fibrillation: SNPs are riding the wave(lets)","year":2006,"lang":"en","type":"letter","venue":"Heart Rhythm","topic":"Renin-Angiotensin System Studies","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Single-nucleotide polymorphism; Personalized medicine; Context (archaeology); Human genome; Medicine; Genetics; Precision medicine; Genomics; Population; Disease; Computational biology; Bioinformatics; Genome; Biology; Genotype; Gene; Internal medicine; Environmental health","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002395453,0.00040146,0.001304253,0.0001492753,0.0001791551,0.00002795494,0.00006923894,0.0005793445,0.00006001013],"category_scores_gemma":[0.0001439802,0.0002728418,0.0006983141,0.0002039418,0.0001767206,0.00002794312,0.0001076961,0.0006005381,0.0001115134],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000981302,"about_ca_system_score_gemma":0.0001194651,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001464781,"about_ca_topic_score_gemma":0.00002397034,"domain_scores_codex":[0.9972888,0.0001822834,0.0008275085,0.0004737449,0.000757177,0.0004705472],"domain_scores_gemma":[0.9978765,0.0004056784,0.0005261375,0.0008679829,0.0002797566,0.00004397768],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002557511,0.00000206791,0.03190057,0.0002668825,0.0001439201,0.001178804,0.00009133821,0.00002083614,0.00001795813,3.435532e-7,0.9653931,0.0009586258],"study_design_scores_gemma":[0.000624446,0.0001054797,0.1456971,0.001250645,0.0004065449,0.007223337,0.00001084699,0.0001471177,0.0001763752,0.0000153391,0.8440781,0.0002647294],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.4997334,0.02132963,0.00003223369,0.4701386,0.004397656,0.002871834,0.0001243641,0.0001713303,0.001200968],"genre_scores_gemma":[0.6540322,0.0005121864,0.003562573,0.1439184,0.1745341,0.00005363593,0.0001796288,0.0005252599,0.02268207],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3262202,"threshold_uncertainty_score":0.9999724,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03880183410852295,"score_gpt":0.2788114406743402,"score_spread":0.2400096065658173,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}