{"id":"W2008221746","doi":"10.1038/nature04185","title":"A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation","year":2005,"lang":"en","type":"article","venue":"Nature","topic":"Wnt/β-catenin signaling in development and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":857,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; Ontario Institute for Cancer Research","funders":"National Institute of General Medical Sciences","keywords":"LRP6; Wnt signaling pathway; Cell biology; Phosphorylation; GSK-3; DKK1; LRP5; Biology; Phosphorylation cascade; Casein kinase 1; Signal transduction; Chemistry; Biochemistry; Protein phosphorylation; Protein kinase A","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006303439679272408,"score_gpt":0.2567902859267809,"score_spread":0.2504868462475086,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}