{"id":"W2008234485","doi":"10.1002/jcb.23301","title":"The activation state of the inositol 1,4,5-trisphosphate receptor regulates the velocity of intracellular Ca2+ waves in bovine aortic endothelial cells","year":2011,"lang":"en","type":"article","venue":"Journal of Cellular Biochemistry","topic":"Protein Kinase Regulation and GTPase Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research; Heart And Stroke Foundation Of Quebec","keywords":"Second messenger system; Extracellular; Endoplasmic reticulum; Inositol; Biophysics; Receptor; Intracellular; Inositol phosphate; Chemistry; Cell biology; Physics; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002414846,0.0001892273,0.0003781915,0.0002717346,0.0001977182,0.0005137273,0.0002357565,0.0003269188,0.0005724953],"category_scores_gemma":[0.0002993097,0.0001177356,0.0002949827,0.0004684861,0.0001392478,0.0003067068,0.0001367554,0.0005420762,0.0002866698],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005015588,"about_ca_system_score_gemma":0.0002531433,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004162374,"about_ca_topic_score_gemma":0.002660693,"domain_scores_codex":[0.9997296,0.00002877266,0.00003626482,0.00006193175,0.00006787667,0.00007558741],"domain_scores_gemma":[0.9997566,0.0000516972,0.00005876323,0.000018514,0.00007266526,0.0000416619],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006700597,0.00001790566,0.0002650021,0.00002083117,0.000002658481,0.00002842834,0.00003191207,0.00004455866,0.9987338,0.00005517488,0.00003774939,0.0006949313],"study_design_scores_gemma":[0.00001457504,0.0001880515,0.03347382,0.00001294583,0.00002726172,0.0001096203,0.0001498311,0.003331014,0.9604715,0.0000745339,0.002129592,0.00001730202],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9864594,0.004342443,0.005710141,0.0001558848,0.00006970517,0.00002140964,0.0007897961,0.00007629013,0.002374905],"genre_scores_gemma":[0.9929041,0.001861141,0.002938248,0.0001021554,0.00001588916,0.00004681396,0.0005754824,0.00002444088,0.001531757],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004162374,"threshold_uncertainty_score":0.008276284,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007510783206848476,"score_gpt":0.2047097509039569,"score_spread":0.1971989676971085,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}