{"id":"W2008263103","doi":"10.1097/fpc.0000000000000008","title":"Expression of UGT2B7 is driven by two mutually exclusive promoters and alternative splicing in human tissues","year":2013,"lang":"en","type":"article","venue":"Pharmacogenetics and Genomics","topic":"Pharmacogenetics and Drug Metabolism","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre hospitalier de l'Université Laval; Université Laval","funders":"Canadian Institutes of Health Research","keywords":"Exon; UGT2B7; Biology; Promoter; Alternative splicing; Glucuronidation; Molecular biology; Kidney; Gene expression; Gene; Genetics; Enzyme; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003038254,0.0003778344,0.0004769038,0.0001958779,0.0002012273,0.00004660199,0.0003082481,0.0001712817,0.0004530892],"category_scores_gemma":[0.000009971868,0.0003826471,0.00006395113,0.0001418954,0.0003180828,0.0001168077,0.0003925989,0.0004790126,0.00001068925],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003125931,"about_ca_system_score_gemma":0.00003915036,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001220401,"about_ca_topic_score_gemma":0.000005525827,"domain_scores_codex":[0.9978778,0.0002457066,0.0006263228,0.0005546183,0.0001726748,0.0005229233],"domain_scores_gemma":[0.9989276,0.0001127507,0.0002932267,0.0001808434,0.000102283,0.000383288],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004639487,0.0001868172,0.01180203,0.00006714396,0.00009713447,0.000009263389,0.004750084,0.0005341709,0.9533579,0.00007478247,0.0007772571,0.02829706],"study_design_scores_gemma":[0.003778662,0.0001056449,0.00180969,0.00002971135,0.0001473481,0.00001259973,0.0002257588,0.01855662,0.9561093,0.00182797,0.01696556,0.0004310996],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9889277,0.008384491,0.0001121401,0.0003888819,0.0003313181,0.0009165609,0.0001883163,0.0000197246,0.0007308706],"genre_scores_gemma":[0.9870379,0.01002455,0.00100713,0.001355857,0.0001981506,0.00007217128,0.00002852035,0.00005218276,0.0002235605],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02786596,"threshold_uncertainty_score":0.9998626,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05437189203628639,"score_gpt":0.4098548268249922,"score_spread":0.3554829347887059,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}