{"id":"W2008270141","doi":"10.1097/qad.0b013e32830efd96","title":"N-Butyldeoxynojirimycin is a broadly effective anti-HIV therapy significantly enhanced by targeted liposome delivery","year":2008,"lang":"en","type":"article","venue":"AIDS","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":68,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research","keywords":"Liposome; Infectivity; Peripheral blood mononuclear cell; Virology; Pharmacology; Viral load; IC50; Drug delivery; Drug; Medicine; Virus; Immunology; Biology; In vitro; Chemistry; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0001281848,0.0002860112,0.000408575,0.0001289795,0.0003583512,0.00001341233,0.000249271,0.0002506688,0.001658697],"category_scores_gemma":[0.00004054976,0.0002276296,0.0001705515,0.000261911,0.0003227908,0.000122703,0.00005406252,0.000338288,0.00769095],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007228454,"about_ca_system_score_gemma":0.00010804,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002697545,"about_ca_topic_score_gemma":0.000002784678,"domain_scores_codex":[0.9981717,0.000351404,0.0002323744,0.0004954788,0.00008496222,0.0006640177],"domain_scores_gemma":[0.9991215,0.0002523115,0.00006920312,0.0003703116,0.0001123625,0.000074305],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000410122,0.0005010168,0.01194709,0.000005597452,0.0006930269,0.00004140116,0.001093367,5.030259e-7,0.9180525,0.00001534734,0.05208067,0.01515938],"study_design_scores_gemma":[0.004183006,0.001660859,0.03342832,0.00001401345,0.00002075408,0.00003603095,0.00009613141,6.237649e-7,0.936181,0.00003302781,0.02408776,0.0002584961],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9874704,0.009079902,0.0002418002,0.0001617216,0.0001735725,0.0007282037,0.0004196779,0.0001251761,0.001599567],"genre_scores_gemma":[0.9891407,0.002365333,0.00008023112,0.0004153488,0.00003237576,0.0001749282,0.0005268164,0.00003007818,0.007234158],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02799292,"threshold_uncertainty_score":0.9992539,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00972846147179814,"score_gpt":0.2364536849672943,"score_spread":0.2267252234954961,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}