{"id":"W2008326745","doi":"10.1182/blood-2004-06-2226","title":"Intracellular kinetics of iron in reticulocytes: evidence for endosome involvement in iron targeting to mitochondria","year":2004,"lang":"en","type":"article","venue":"Blood","topic":"Iron Metabolism and Disorders","field":"Medicine","cited_by":120,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"","keywords":"Endosome; Ferrochelatase; Biochemistry; Chemistry; Bafilomycin; Mitochondrion; Endocytosis; Cell biology; Ferritin; Vesicle; Biophysics; Protoporphyrin IX; Intracellular; Heme; Biology; Autophagy; Membrane; Cell; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002344785,0.0001425269,0.0003161127,0.000202115,0.00001189549,0.000006503774,0.0001086453,0.00008360969,0.00001927722],"category_scores_gemma":[0.000737951,0.0001364206,0.00005925879,0.0002845412,0.00003690261,0.00005922542,0.00004283856,0.0001148278,0.000007394082],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005659097,"about_ca_system_score_gemma":0.00006431049,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002157287,"about_ca_topic_score_gemma":0.0001495038,"domain_scores_codex":[0.9986718,0.0000273318,0.0004745421,0.0002782707,0.0002325417,0.000315566],"domain_scores_gemma":[0.9994471,0.00008040281,0.00008069101,0.000244218,0.00005064223,0.0000969163],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002774449,0.001474466,0.01833588,0.0009364016,0.000004990851,0.00002911139,0.002513044,0.0007501161,0.9745515,0.000690522,0.00005759043,0.0003789402],"study_design_scores_gemma":[0.01684005,0.001283307,0.02410118,0.00136763,0.0001764462,0.000004127958,0.001646934,0.00002051898,0.9529818,0.0007394847,0.0005563651,0.0002821955],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9913801,0.005595826,0.0007731211,0.0008462791,0.0001188376,0.001178415,0.000004487622,0.00001416864,0.00008876636],"genre_scores_gemma":[0.9718585,0.0002588938,0.02736178,0.0002553452,0.0001005589,0.00009430349,0.00001545979,0.00002099753,0.00003414363],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02658866,"threshold_uncertainty_score":0.5563068,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02445356779532205,"score_gpt":0.281827063362233,"score_spread":0.257373495566911,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}