{"id":"W2008362068","doi":"10.1016/j.bbamcr.2012.08.004","title":"The dynamin GTPase OPA1: More than mitochondria?","year":2012,"lang":"en","type":"review","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Cell Research","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":113,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval","funders":"Fonds de Recherche du Québec - Santé; Union Nationale des Aveugles et Déficients Visuels; Conseil Régional Midi-Pyrénées; Canadian Institutes of Health Research; Centre National de la Recherche Scientifique; Ligue Contre le Cancer","keywords":"Cell biology; Dynamin; GTPase; mitochondrial fusion; Mitochondrial fission; Biology; Mitochondrion; Intermembrane space; Mitophagy; Cytosol; MFN1; Biochemistry; Mitochondrial DNA; Cell; Bacterial outer membrane; Endocytosis; Apoptosis; Autophagy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.001704992,0.001181768,0.001383879,0.0004194519,0.0008077263,0.0003839096,0.002468891,0.001522977,0.00005702646],"category_scores_gemma":[0.0003539052,0.0008648218,0.001549036,0.001039648,0.001046283,0.00001556144,0.001593941,0.002167595,0.0007200756],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001387344,"about_ca_system_score_gemma":0.001147364,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004501268,"about_ca_topic_score_gemma":0.00002444251,"domain_scores_codex":[0.9904954,0.003291669,0.001041331,0.001882482,0.001277074,0.002012066],"domain_scores_gemma":[0.9946585,0.0004058529,0.0005223705,0.003257943,0.0004517655,0.0007035439],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003036048,0.0006523753,3.080473e-7,0.002974183,0.0006647789,0.0001114189,0.0001275125,9.270838e-7,0.8795315,0.0004797862,0.02086873,0.09428487],"study_design_scores_gemma":[0.0004027905,0.0004410228,0.000001949435,0.0004082431,0.0003845255,0.00005426713,0.00006632853,0.000005493643,0.1303018,0.0000364117,0.8670535,0.0008436188],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00437445,0.9838361,0.000202502,0.000639088,0.001675717,0.002745825,0.0003069633,0.00006811137,0.006151316],"genre_scores_gemma":[0.003349074,0.9813747,0.000428751,0.0002334073,0.001851359,0.0008286356,0.002550115,0.0003642077,0.009019758],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8461848,"threshold_uncertainty_score":0.9997733,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06788095110498486,"score_gpt":0.3815278042113242,"score_spread":0.3136468531063393,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}