{"id":"W2008409938","doi":"10.1016/j.jamcollsurg.2004.05.073","title":"Stilbazulenyl nitrone (STAZN), a novel azulenyl nitrone antioxidant prevents lung injury following hemorrhagic shock and alters TLR4 distribution in alveolar macrophages","year":2004,"lang":"en","type":"article","venue":"Journal of the American College of Surgeons","topic":"Respiratory Support and Mechanisms","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network","funders":"","keywords":"Medicine; Nitrone; Distribution (mathematics); Antioxidant; Lung; TLR4; Shock (circulatory); Alveolar macrophage; Pharmacology; Macrophage; Immunology; Inflammation; Biochemistry; Internal medicine; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006573257,0.000236945,0.0001997604,0.0001915896,0.0001107173,0.0001024538,0.0001800792,0.0001912629,0.001016969],"category_scores_gemma":[0.00005852592,0.00008127373,0.0001573462,0.00009014516,0.0001647343,0.0001842046,0.0001231772,0.0003280087,0.0001376033],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001067447,"about_ca_system_score_gemma":0.0001529268,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003268811,"about_ca_topic_score_gemma":0.0006344374,"domain_scores_codex":[0.9999659,0.000005718948,0.000003637342,0.000006952168,0.000008719954,0.00000903712],"domain_scores_gemma":[0.9999684,0.000002669834,0.00001371007,0.000002402661,0.000003851617,0.000009032457],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004631965,0.0001079118,0.0001490867,0.00009604499,0.000008476954,0.0000355066,0.00001303554,0.00005367941,0.9958169,0.00005519172,0.00006539157,0.00313557],"study_design_scores_gemma":[0.0001023992,0.003721924,0.003621276,0.00001458852,0.00003753863,0.0002677705,0.00002935729,0.0005566455,0.9889823,0.00004109533,0.002619729,0.00000532826],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9927701,0.003729362,0.002182518,0.0001243887,0.00004497469,0.0000361397,0.0001147235,0.0001174263,0.000880275],"genre_scores_gemma":[0.9946055,0.002234255,0.001425272,0.00004423622,0.00001509693,0.00002938444,0.0001853249,0.000006028143,0.001454905],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001016969,"threshold_uncertainty_score":0.003402114,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0083469645945832,"score_gpt":0.2587953801507571,"score_spread":0.2504484155561739,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}