{"id":"W2008455207","doi":"10.1021/ol051286l","title":"Pd-Catalyzed Tandem C−N/C−C Coupling of <i>gem</i>-Dihalovinyl Systems:  A Modular Synthesis of 2-Substituted Indoles","year":2005,"lang":"en","type":"article","venue":"Organic Letters","topic":"Catalytic C–H Functionalization Methods","field":"Chemistry","cited_by":168,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Chemistry; Tandem; Catalysis; Reagent; Alkyl; Combinatorial chemistry; Coupling (piping); Medicinal chemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004562062,0.0002433361,0.0005303177,0.0001405621,0.00006302521,0.00002513329,0.0003547324,0.000161204,0.00114399],"category_scores_gemma":[0.0007025823,0.0002556452,0.0001484855,0.0004165382,0.0001586816,0.0001623671,0.00008513948,0.0001615737,0.00003659784],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002349879,"about_ca_system_score_gemma":0.000125459,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000715438,"about_ca_topic_score_gemma":0.000009003499,"domain_scores_codex":[0.9980584,0.00002423952,0.0007645953,0.0003717861,0.0005177684,0.0002631943],"domain_scores_gemma":[0.9981374,0.0004607802,0.0004980933,0.0006566526,0.0001575234,0.00008956347],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003096318,0.00008302998,0.001987441,0.0003731363,0.0001882934,0.000004576026,0.0001374275,0.006575765,0.9896649,0.0001744294,0.0005587594,0.0002212729],"study_design_scores_gemma":[0.0007127025,0.000002720873,0.0002992381,0.0002674158,0.0001847184,0.00002922187,0.000185994,0.006423311,0.9905604,0.000006900535,0.001070676,0.0002567643],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.973732,0.0004177455,0.02449863,0.000604037,0.0001854946,0.0001248214,0.00006398794,0.0001153431,0.0002579229],"genre_scores_gemma":[0.997529,0.00002703845,0.001793076,0.000125249,0.0002919707,0.00002055349,0.00006900752,0.00006120579,0.00008292585],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02379696,"threshold_uncertainty_score":0.9999896,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01388034176599686,"score_gpt":0.2317787072766972,"score_spread":0.2178983655107004,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}