{"id":"W2008473687","doi":"10.1007/s00125-010-1986-3","title":"New aspects of an old drug: metformin as a glucagon-like peptide 1 (GLP-1) enhancer and sensitiser","year":2010,"lang":"en","type":"letter","venue":"Diabetologia","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":88,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Metformin; Incretin; Internal medicine; Glucagon-like peptide-1; Endocrinology; Medicine; Receptor; Type 2 diabetes; Insulin; Diabetes mellitus; Pharmacology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002049371,0.0005999214,0.001292071,0.0002747509,0.00005443238,0.00005072948,0.0002147472,0.001100146,0.0007972196],"category_scores_gemma":[0.00007130073,0.0004911376,0.0002182942,0.0001949202,0.0001828768,0.0001652178,0.0001836683,0.001565372,0.0001863251],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007525378,"about_ca_system_score_gemma":0.0001879468,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004358075,"about_ca_topic_score_gemma":0.0001271879,"domain_scores_codex":[0.9975002,0.00006509652,0.0004601001,0.0007945833,0.0004741498,0.0007058445],"domain_scores_gemma":[0.9982324,0.0001457599,0.0003187427,0.0009369808,0.0001142486,0.0002518262],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005611562,0.0001514395,0.001416989,0.0005295665,0.0009290306,0.001872822,0.0002382598,1.42039e-7,0.001788824,0.000412095,0.9518339,0.0407708],"study_design_scores_gemma":[0.002470311,0.0009127543,0.004423758,0.0003922441,0.001987357,0.00005964169,0.00005868092,0.00001477722,0.02845012,0.001369879,0.9591865,0.0006740041],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"commentary","genre_scores_codex":[0.8657622,0.001560679,0.00001318003,0.08034629,0.001560604,0.00182831,0.00005886599,0.0002668491,0.04860301],"genre_scores_gemma":[0.08117361,0.0008034168,0.01578842,0.6621516,0.00524874,0.0002690979,0.003743393,0.0003987201,0.230423],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.7845886,"threshold_uncertainty_score":0.999754,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008963569399374352,"score_gpt":0.2481675024254011,"score_spread":0.2392039330260268,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}