{"id":"W2008589966","doi":"10.3762/bjoc.7.114","title":"One-pot Diels–Alder cycloaddition/gold(I)-catalyzed 6-<i>endo-dig</i> cyclization for the synthesis of the complex bicyclo[3.3.1]alkenone framework","year":2011,"lang":"en","type":"article","venue":"Beilstein Journal of Organic Chemistry","topic":"Catalytic Alkyne Reactions","field":"Chemistry","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; University of Ottawa; Ontario Innovation Trust","keywords":"Chemistry; Bicyclic molecule; Cycloaddition; Ketone; Catalysis; Cycloisomerization; Diels–Alder reaction; Stereochemistry; Combinatorial chemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000398225,0.0003528867,0.0006038339,0.00004679864,0.0002935911,0.0000536255,0.001313337,0.0003262343,0.005279064],"category_scores_gemma":[0.002046141,0.0002570155,0.0006120135,0.0004580324,0.0003833194,0.0002013676,0.0002009019,0.0006929518,0.00001173526],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002337683,"about_ca_system_score_gemma":0.000359066,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002168222,"about_ca_topic_score_gemma":0.000007461243,"domain_scores_codex":[0.9973667,0.00002883353,0.001213035,0.0003163747,0.0006687817,0.0004062963],"domain_scores_gemma":[0.9949251,0.00148113,0.001732996,0.001153847,0.000535952,0.0001709733],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001928763,0.0005690707,0.0004806993,0.0004026848,0.0007600248,0.00000558378,0.0004691094,0.0000119348,0.9919244,0.0001069894,0.002051414,0.003025197],"study_design_scores_gemma":[0.0009261403,0.00001596472,0.001373153,0.0005842136,0.0009086544,0.0004061433,0.0009605086,0.00005286907,0.9893396,0.001539424,0.003587375,0.0003059604],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9517826,0.001741106,0.01726806,0.003438096,0.001014812,0.0007772039,0.0008924801,0.0001686699,0.02291695],"genre_scores_gemma":[0.9962783,0.0002140925,0.001484346,0.00006832443,0.0008569983,0.00003652955,0.00003574419,0.0000971692,0.0009284557],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04449572,"threshold_uncertainty_score":0.9999882,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03381533293721702,"score_gpt":0.2379582164491041,"score_spread":0.2041428835118871,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}