{"id":"W2008605395","doi":"10.1016/j.yexcr.2011.03.013","title":"Soluble growth factors stimulate spermatogonial stem cell divisions that maintain a stem cell pool and produce progenitors in vitro","year":2011,"lang":"en","type":"article","venue":"Experimental Cell Research","topic":"Sperm and Testicular Function","field":"Medicine","cited_by":49,"is_retracted":false,"has_abstract":false,"ca_institutions":"Royal Victoria Hospital; McGill University","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; McGill University Health Centre","keywords":"Glial cell line-derived neurotrophic factor; Biology; Cell biology; Progenitor cell; Stem cell; Neurotrophic factors; Fibroblast growth factor; Cell division; Population; Progenitor; Somatic cell; Growth factor; Cell; Immunology; Genetics; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003640064,0.0005812478,0.0003581455,0.0008924761,0.0002135817,0.0004704348,0.00019936,0.0002520386,0.003428861],"category_scores_gemma":[0.0003099689,0.000193777,0.0004988232,0.000563886,0.0004342456,0.0002173985,0.0003771495,0.0006495094,0.0007896737],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004079103,"about_ca_system_score_gemma":0.0004098174,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000996584,"about_ca_topic_score_gemma":0.003182148,"domain_scores_codex":[0.9997849,0.00005378641,0.00001787866,0.00002688591,0.00005468346,0.00006191935],"domain_scores_gemma":[0.9994272,0.0002670023,0.00006107161,0.00004028453,0.0000517203,0.0001527443],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007994918,0.0002510311,0.0007060986,0.0001872263,0.00002146559,0.0001338041,0.00009569353,0.0001507682,0.9890591,0.0006400874,0.0005065691,0.007448609],"study_design_scores_gemma":[0.0001820443,0.001078457,0.004534364,0.000025272,0.00004524644,0.0002155205,0.00007745586,0.0006753902,0.9862162,0.0002226628,0.006720286,0.000007142776],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9687173,0.007781757,0.008145953,0.0004211336,0.0003316206,0.0002027272,0.001187914,0.0002643305,0.01294723],"genre_scores_gemma":[0.9760181,0.003427941,0.00783716,0.0001603397,0.0002779902,0.0001080116,0.002174527,0.00009394904,0.009902031],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003428861,"threshold_uncertainty_score":0.01147062,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09775773301669005,"score_gpt":0.3274575767397518,"score_spread":0.2296998437230617,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}