{"id":"W2008640926","doi":"10.1002/cbic.201300739","title":"Simultaneous Inhibition Assay for Human and Microbial Kinases via MALDI‐MS/MS","year":2014,"lang":"en","type":"article","venue":"ChemBioChem","topic":"Mass Spectrometry Techniques and Applications","field":"Chemistry","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Kinase; Chemistry; Enzyme; Biochemistry; Antimicrobial; Small molecule","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001119155,0.0001737997,0.0001770636,0.00003570014,0.0001744798,0.00005163865,0.0001144647,0.0001732404,0.0008139997],"category_scores_gemma":[0.00008931419,0.0001850354,0.00007637937,0.00007924908,0.00007720595,0.00003207586,0.00006184453,0.000119918,0.000008648076],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005122979,"about_ca_system_score_gemma":0.000007621623,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002720779,"about_ca_topic_score_gemma":0.000007872171,"domain_scores_codex":[0.9991119,0.000005481301,0.0001983612,0.0003605755,0.00008208158,0.000241587],"domain_scores_gemma":[0.9993005,0.0001349493,0.00009720545,0.0003184157,0.0000619676,0.00008698279],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000008955694,0.00008423316,0.00005497871,0.0001497346,0.00000930478,8.713164e-7,0.00001726603,5.018436e-7,0.9903611,0.004750155,0.00212183,0.002441062],"study_design_scores_gemma":[0.0003930971,0.0000387747,0.00001125103,0.00003104421,0.0000243797,0.00001840973,0.000009503096,0.0003831228,0.9588982,0.00677026,0.03319824,0.0002237188],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9601172,0.00005196273,0.006926709,0.0003107264,0.00001642675,0.000198717,0.00006049539,0.0003035445,0.03201422],"genre_scores_gemma":[0.9943135,0.000007347626,0.002888258,0.0001099211,0.0003460339,0.0001304812,0.0002923842,0.00003453,0.001877526],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03419632,"threshold_uncertainty_score":0.8912726,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008255411491578588,"score_gpt":0.2466438810460912,"score_spread":0.2383884695545126,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}