{"id":"W2008640926","doi":"10.1002/cbic.201300739","title":"Simultaneous Inhibition Assay for Human and Microbial Kinases via MALDI‐MS/MS","year":2014,"lang":"en","type":"article","venue":"ChemBioChem","topic":"Mass Spectrometry Techniques and Applications","field":"Chemistry","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Kinase; Chemistry; Enzyme; Biochemistry; Antimicrobial; Small molecule","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002054253,0.001850888,0.0009232268,0.0008682018,0.0004012467,0.0006671593,0.0007775045,0.0009900404,0.002196343],"category_scores_gemma":[0.001408227,0.000541472,0.000546005,0.0005995921,0.0004633079,0.0007158103,0.0007707837,0.0016749,0.001782487],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005050162,"about_ca_system_score_gemma":0.0007267306,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004791188,"about_ca_topic_score_gemma":0.001054551,"domain_scores_codex":[0.9980922,0.0002800457,0.0001334436,0.0004701396,0.000882741,0.0001413934],"domain_scores_gemma":[0.9990971,0.0003210263,0.0001338101,0.00007735148,0.0002724325,0.00009835455],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006280754,0.00003469716,0.0001460124,0.00005953142,0.0000190758,0.00001786302,0.00001441837,0.00005270501,0.9964449,0.00006782926,0.0001221279,0.002957944],"study_design_scores_gemma":[0.000009808809,0.0001377822,0.0005827711,0.000005729225,0.0000235173,0.0001376633,0.00000931073,0.001154509,0.9960091,0.00004180128,0.001879188,0.00000875758],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.3910599,0.009825802,0.5800009,0.0008547733,0.0004109871,0.001183141,0.002740043,0.003145246,0.01077927],"genre_scores_gemma":[0.4448426,0.009150962,0.5266827,0.0008491022,0.0001276113,0.002154259,0.004183143,0.0003260033,0.01168364],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.002196343,"threshold_uncertainty_score":0.01086408,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008255411491578588,"score_gpt":0.2466438810460912,"score_spread":0.2383884695545126,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}