{"id":"W2008712084","doi":"10.1016/j.tig.2012.04.002","title":"Epigenetics of major psychosis: progress, problems and perspectives","year":2012,"lang":"en","type":"review","venue":"Trends in Genetics","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":101,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre for Addiction and Mental Health","funders":"National Institute of Mental Health; Canadian Institutes of Health Research","keywords":"Epigenetics; Biology; Histone; Schizophrenia (object-oriented programming); DNA methylation; Disease; Neuroscience; Epigenesis; Genetics; Computational biology; Bioinformatics; Psychology; Psychiatry; Medicine; Gene; Pathology; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00123537,0.0008693554,0.001850275,0.001057375,0.0003101722,0.00129725,0.001045153,0.001693145,0.001948959],"category_scores_gemma":[0.001043142,0.0002569596,0.0003156412,0.00156253,0.001194174,0.001835738,0.000983962,0.002027927,0.0007830809],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008741311,"about_ca_system_score_gemma":0.001586342,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001485614,"about_ca_topic_score_gemma":0.003412364,"domain_scores_codex":[0.999797,0.00005398903,0.00002780278,0.00003956259,0.00005932216,0.00002231312],"domain_scores_gemma":[0.9994588,0.000296242,0.00006037382,0.00001571659,0.0001117366,0.00005704408],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001718359,0.00005309137,0.0005406542,0.008233947,0.0001113546,0.0003926151,0.0001063569,0.0003440942,0.001595781,0.008693552,0.04143401,0.9383227],"study_design_scores_gemma":[0.00005759322,0.0001011097,0.002530302,0.004693051,0.0002132747,0.002233284,0.0002683346,0.0001997296,0.0005390559,0.01234148,0.9767756,0.00004721405],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00006469487,0.9983816,0.00009300357,0.00101143,0.0002080651,9.278439e-7,0.000007494491,0.000003077983,0.0002296791],"genre_scores_gemma":[0.0007317425,0.9978599,0.0001469678,0.0004477053,0.0005906068,0.000002849268,0.00001155153,8.953281e-7,0.0002078435],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001948959,"threshold_uncertainty_score":0.006533325,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07892914905379154,"score_gpt":0.3595274313488492,"score_spread":0.2805982822950577,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}