{"id":"W2008754716","doi":"10.1006/excr.2001.5222","title":"Modulation of Caspase-3 Activity by Zinc Ions and by the Cell Redox State","year":2001,"lang":"en","type":"article","venue":"Experimental Cell Research","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval","funders":"","keywords":"DNA fragmentation; Apoptotic DNA fragmentation; Apoptosis; Biology; ICAD; Hydrogen peroxide; Fragmentation (computing); Caspase; Molecular biology; DNA; Programmed cell death; Cleavage (geology); Cell biology; Chelation; DNA damage; Biophysics; Biochemistry; Chemistry; Inorganic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004241614,0.0004292455,0.0004381579,0.0003216888,0.0003174631,0.0009601122,0.000504776,0.000488426,0.001424678],"category_scores_gemma":[0.0005019591,0.0002412868,0.0002890619,0.0003667425,0.0006951811,0.0007466036,0.0003142692,0.000697549,0.0002448834],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007609298,"about_ca_system_score_gemma":0.0002961157,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001065186,"about_ca_topic_score_gemma":0.001462864,"domain_scores_codex":[0.9997492,0.0000531065,0.00002534329,0.00004680325,0.00003976189,0.00008568326],"domain_scores_gemma":[0.9997526,0.00006956192,0.00005417287,0.00004342036,0.00003303619,0.00004724099],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005068695,0.0000630112,0.0007088064,0.00005567071,0.00001657128,0.0001238649,0.00004308349,0.0001064039,0.9902133,0.0007398304,0.00007878122,0.002781997],"study_design_scores_gemma":[0.0001585073,0.0002495408,0.002935951,0.000005209241,0.00002454094,0.000200793,0.00004988937,0.000867484,0.9940526,0.0005234495,0.0009205997,0.00001136413],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9894267,0.005045885,0.003221025,0.0004580318,0.0000847592,0.00002666647,0.0003275651,0.00006357337,0.001345673],"genre_scores_gemma":[0.9960999,0.001271584,0.001078321,0.00004909584,0.00002592998,0.00001548148,0.0001910139,0.00001371413,0.001254917],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001424678,"threshold_uncertainty_score":0.00552094,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02403546948128049,"score_gpt":0.3301654173871278,"score_spread":0.3061299479058474,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}