{"id":"W2008754716","doi":"10.1006/excr.2001.5222","title":"Modulation of Caspase-3 Activity by Zinc Ions and by the Cell Redox State","year":2001,"lang":"en","type":"article","venue":"Experimental Cell Research","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval","funders":"","keywords":"DNA fragmentation; Apoptotic DNA fragmentation; Apoptosis; Biology; ICAD; Hydrogen peroxide; Fragmentation (computing); Caspase; Molecular biology; DNA; Programmed cell death; Cleavage (geology); Cell biology; Chelation; DNA damage; Biophysics; Biochemistry; Chemistry; Inorganic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000311079,0.00008523087,0.00006913554,0.00002828708,0.0002321182,0.00002414494,0.0001001214,0.00007377511,0.00005006052],"category_scores_gemma":[0.000005886463,0.00006618556,0.00003250618,0.00009930885,0.0001949615,0.000006730797,0.0001364933,0.000099707,0.000003660314],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002625837,"about_ca_system_score_gemma":0.00002408562,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003163337,"about_ca_topic_score_gemma":0.00001937946,"domain_scores_codex":[0.9990565,0.0001385036,0.0001018599,0.0002373659,0.000242767,0.0002230189],"domain_scores_gemma":[0.9995859,0.00001989435,0.00003804577,0.0002246575,0.00005888591,0.00007259515],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008624836,0.0001922057,0.000114746,0.000008204947,0.000004743425,8.769168e-7,0.0001804899,0.0000210077,0.9923624,0.000008847953,0.004565706,0.002454505],"study_design_scores_gemma":[0.0003558395,0.000303604,0.0003730478,0.000002802554,0.000001644509,0.000003579109,0.0003290767,0.0006094796,0.9845181,0.00005669911,0.01337377,0.00007235204],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9919543,0.003782765,0.0005434283,0.00005660266,0.00002799495,0.000241624,0.00003080589,0.000003678931,0.003358768],"genre_scores_gemma":[0.9884459,0.0008582435,0.00007750272,0.000009460411,0.00003232182,0.00002135743,0.00008545227,0.00001448568,0.01045532],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008808067,"threshold_uncertainty_score":0.2698969,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02403546948128049,"score_gpt":0.3301654173871278,"score_spread":0.3061299479058474,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}