{"id":"W2008770122","doi":"10.1182/blood-2013-11-536219","title":"c-Myc regulates expression of NKG2D ligands ULBP1/2/3 in AML and modulates their susceptibility to NK-mediated lysis","year":2014,"lang":"en","type":"article","venue":"Blood","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":69,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Cancer Research; Institut National Du Cancer","keywords":"Cytarabine; NKG2D; Myeloid leukemia; Cancer research; Biology; Leukemia; K562 cells; Natural killer cell; Myeloid; Cell culture; Immunology; Cytotoxicity; Biochemistry; In vitro","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005019903,0.0001423382,0.0001993931,0.0002466671,0.0001535623,0.0002613719,0.00008676102,0.0001812157,0.001221306],"category_scores_gemma":[0.00009027772,0.0001053815,0.00012744,0.0001635112,0.0001465553,0.0001045581,0.0001505515,0.0003526312,0.0003152685],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002308214,"about_ca_system_score_gemma":0.00009787814,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005035503,"about_ca_topic_score_gemma":0.0005245001,"domain_scores_codex":[0.9999273,0.000008222098,0.000006562646,0.00001337371,0.00001631385,0.00002817945],"domain_scores_gemma":[0.999945,0.000006133418,0.00001669951,0.000003850051,0.000006936883,0.00002139331],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003255377,0.00002775371,0.001589188,0.00002378413,0.000003545009,0.0001114628,0.00002748332,0.00003210865,0.9964748,0.0000445966,0.00005307096,0.00128668],"study_design_scores_gemma":[0.00008395428,0.0004360169,0.2563709,0.00001553188,0.00003900035,0.001328776,0.000219582,0.00181959,0.7334107,0.0001523401,0.006109301,0.00001441757],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971293,0.001493686,0.0003776782,0.00005139373,0.00001090677,0.0000148234,0.000287521,0.00002987678,0.0006048779],"genre_scores_gemma":[0.9974297,0.0006641969,0.0002617095,0.0000374132,0.000007947466,0.00002363222,0.0003296133,0.00000806621,0.001237815],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001221306,"threshold_uncertainty_score":0.00408566,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006254586654919044,"score_gpt":0.2022971960279557,"score_spread":0.1960426093730367,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}