{"id":"W2008794157","doi":"10.1074/jbc.m112.348052","title":"Yeast Adaptor Protein, Nbp2p, Is Conserved Regulator of Fungal Ptc1p Phosphatases and Is Involved in Multiple Signaling Pathways","year":2012,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Fungal and yeast genetics research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Biology; SH3 domain; Schizosaccharomyces pombe; Signal transducing adaptor protein; Neurospora crassa; Conserved sequence; Saccharomyces cerevisiae; Cell biology; Protein domain; Signal transduction; Phosphatase; Fungal protein; Yeast; Genetics; Proto-oncogene tyrosine-protein kinase Src; Gene; Phosphorylation; Peptide sequence; Mutant","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006229804,0.0008981276,0.0003204455,0.0003189262,0.0004351265,0.0003609278,0.000199876,0.0003118303,0.001227258],"category_scores_gemma":[0.00009193373,0.000144799,0.0002470017,0.0003213293,0.0001794635,0.0002012826,0.0004722061,0.0003159474,0.001003633],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004061981,"about_ca_system_score_gemma":0.0002666489,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0010332,"about_ca_topic_score_gemma":0.0007432551,"domain_scores_codex":[0.9998778,0.000008106354,0.00000674706,0.00004606845,0.00004237852,0.0000187566],"domain_scores_gemma":[0.9999256,0.000004319704,0.00002156828,0.000005149534,0.00001272398,0.00003056664],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002376414,0.00002581269,0.002113454,0.0001387025,0.00001533413,0.0007466447,0.00002625847,0.0002440158,0.9887303,0.0003619994,0.0008765868,0.006483357],"study_design_scores_gemma":[0.00009179728,0.000216469,0.08781974,0.00003380159,0.00008158619,0.005746525,0.0001172795,0.01030557,0.8504676,0.0007500065,0.04432926,0.00004035225],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9545001,0.009997433,0.02100072,0.0002949092,0.0002040312,0.00008358056,0.004505713,0.002416887,0.0069967],"genre_scores_gemma":[0.9816099,0.001790771,0.003777822,0.00008428098,0.00002833808,0.00006069055,0.005502935,0.00007593775,0.007069407],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001227258,"threshold_uncertainty_score":0.004105568,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05291267703641275,"score_gpt":0.2606753042534065,"score_spread":0.2077626272169937,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}