{"id":"W2008817826","doi":"10.1038/embor.2011.48","title":"Structural analysis of 5′‐mRNA–cap interactions with the human AGO2 MID domain","year":2011,"lang":"en","type":"article","venue":"EMBO Reports","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; Boehringer Ingelheim Fonds; Howard Hughes Medical Institute","keywords":"Messenger RNA; Domain (mathematical analysis); Cell biology; Biology; Computational biology; Argonaute; Genetics; RNA; Gene; RNA interference","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001618753,0.00007768662,0.0001270646,0.00006888675,0.0001053806,0.00001143302,0.00009847763,0.00003262962,0.0001559573],"category_scores_gemma":[0.00001986077,0.00004658736,0.0001122432,0.0001872073,0.00009083947,0.000003614399,0.00005475975,0.00007652268,6.069763e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00000660657,"about_ca_system_score_gemma":0.00003091529,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003683727,"about_ca_topic_score_gemma":0.001002143,"domain_scores_codex":[0.9993019,0.00003754059,0.0001831717,0.0001926031,0.0001362837,0.0001485534],"domain_scores_gemma":[0.9992507,0.000005373758,0.000155543,0.000452801,0.00008329795,0.00005232741],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003697294,0.00002287008,0.05842626,0.000005025428,0.000857366,0.0000879796,0.0002616202,0.00004476849,0.9391361,0.00006075546,0.0008180814,0.0002422182],"study_design_scores_gemma":[0.0002707178,0.0003372566,0.346872,0.00001607704,0.0004437761,0.0003359602,0.0007271828,0.0000635056,0.6436494,0.0002778595,0.006732575,0.0002737274],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945618,0.00006566605,0.0001758484,0.00005392328,0.00003635233,0.00007975484,0.000002525865,0.000004564381,0.005019553],"genre_scores_gemma":[0.9971328,0.000003495306,0.0002603749,0.0000326912,0.00004076253,0.000009174953,0.00005317449,0.00000776848,0.002459743],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2954867,"threshold_uncertainty_score":0.1899778,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01956083489627645,"score_gpt":0.2917958539869189,"score_spread":0.2722350190906425,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}