{"id":"W2008831444","doi":"10.1016/j.lfs.2008.02.018","title":"Epigallocatechin-3-O-gallate inhibits TNFα-induced monocyte chemotactic protein-1 production from vascular endothelial cells","year":2008,"lang":"en","type":"article","venue":"Life Sciences","topic":"Atherosclerosis and Cardiovascular Diseases","field":"Immunology and Microbiology","cited_by":65,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Tumor necrosis factor alpha; Wortmannin; Monocyte; Protein kinase B; Chemistry; Pharmacology; LY294002; Epigallocatechin gallate; PI3K/AKT/mTOR pathway; Phosphorylation; Cancer research; Medicine; Biochemistry; Internal medicine; Signal transduction; Polyphenol","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002473177,0.0008465265,0.000571615,0.0004494943,0.0002547833,0.0004675145,0.0003426273,0.0003865554,0.001373513],"category_scores_gemma":[0.000310406,0.0002247384,0.0006324599,0.0002721027,0.0003178407,0.0002720298,0.0003145678,0.001089142,0.0008208221],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002607136,"about_ca_system_score_gemma":0.0005008813,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001078817,"about_ca_topic_score_gemma":0.001205721,"domain_scores_codex":[0.9997479,0.00005015143,0.00002702689,0.00001608308,0.00003924975,0.0001195533],"domain_scores_gemma":[0.9998128,0.00004466303,0.00002531575,0.00004060933,0.00002492476,0.00005179209],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003607472,0.0003080417,0.0002923866,0.0001255005,0.00002887635,0.0002334381,0.00004634639,0.0001321258,0.9915078,0.00008398492,0.0001903334,0.003443741],"study_design_scores_gemma":[0.0003424048,0.001937617,0.007928858,0.00001737527,0.00008248541,0.000353962,0.000061717,0.000735761,0.9869276,0.0000925131,0.001507339,0.0000123745],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9929948,0.002632553,0.001458766,0.0003442122,0.0001772367,0.00004252658,0.000421604,0.0001170811,0.001811291],"genre_scores_gemma":[0.9935602,0.001713754,0.0007901497,0.0001970259,0.00008279776,0.00004439112,0.0009680493,0.00002231781,0.002621337],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001373513,"threshold_uncertainty_score":0.004594803,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03043220706483235,"score_gpt":0.2220999262416943,"score_spread":0.191667719176862,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}