{"id":"W2008913755","doi":"10.1038/nrmicro773","title":"Psychrophilic enzymes: hot topics in cold adaptation","year":2003,"lang":"en","type":"review","venue":"Nature Reviews Microbiology","topic":"Polar Research and Ecology","field":"Environmental Science","cited_by":1146,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"European Commission; Polar Knowledge Canada","keywords":"Psychrophile; Biology; Extreme environment; Cold climate; Extremophile; Adaptation (eye); Ecosystem; Ecology; Mesophile; Astrobiology; Thermophile; Enzyme; Bacteria; Biochemistry; Genetics; Meteorology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001500237,0.002273215,0.003358841,0.002478021,0.0004534709,0.002072521,0.001482218,0.002349073,0.003544672],"category_scores_gemma":[0.001358301,0.0004789976,0.0005702994,0.0049572,0.001203378,0.00340931,0.001261656,0.00252205,0.004494623],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008153322,"about_ca_system_score_gemma":0.001455585,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000974806,"about_ca_topic_score_gemma":0.00225645,"domain_scores_codex":[0.9995989,0.00005268279,0.00005616987,0.00008602751,0.0001640436,0.00004222166],"domain_scores_gemma":[0.9988055,0.0004189331,0.0001526086,0.00004231217,0.0003902166,0.0001904056],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001328632,0.00005424961,0.0002462044,0.009525748,0.00008773065,0.0002076811,0.00006293544,0.0002602285,0.002879235,0.00194362,0.07641337,0.9081861],"study_design_scores_gemma":[0.00003023587,0.00005277163,0.0006035999,0.001352314,0.00009225496,0.0007811458,0.00006918645,0.00004820242,0.000442804,0.001518355,0.9949898,0.00001935749],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00006324307,0.9981619,0.000182704,0.0004008206,0.0006373186,0.000002810239,0.00001455294,0.0000097792,0.0005268145],"genre_scores_gemma":[0.0003446133,0.9977601,0.000228021,0.0003878147,0.0007260495,0.000004787868,0.00003798075,0.000001902739,0.0005087717],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003544672,"threshold_uncertainty_score":0.01185805,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04592942899585425,"score_gpt":0.3497369791099314,"score_spread":0.3038075501140772,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}