{"id":"W2008945784","doi":"10.3899/jrheum.111549","title":"Beneficial Effect of Interleukin 1 Inhibition with Anakinra in Adult-onset Still’s Disease. An Open, Randomized, Multicenter Study","year":2012,"lang":"en","type":"article","venue":"The Journal of Rheumatology","topic":"Autoimmune and Inflammatory Disorders Research","field":"Medicine","cited_by":163,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Anakinra; Medicine; Internal medicine; Prednisolone; Adult-onset Still's disease; Clinical endpoint; Open label; Rheumatology; Refractory (planetary science); Gastroenterology; Randomized controlled trial; Disease; Surgery","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003849705,0.0001553814,0.001181737,0.0002785609,0.00004436573,0.0000124441,0.0002777656,0.00005652088,0.0001042092],"category_scores_gemma":[0.000750073,0.00007784209,0.00008865161,0.0001635469,0.0002586537,0.0003586159,0.0001186924,0.0004173287,0.000006756501],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004459199,"about_ca_system_score_gemma":0.0001447736,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005143647,"about_ca_topic_score_gemma":0.0002631458,"domain_scores_codex":[0.9965054,0.001889562,0.0008974356,0.00008936672,0.0003346234,0.0002836307],"domain_scores_gemma":[0.9982425,0.0005434486,0.0005777453,0.0002771275,0.0002177546,0.000141442],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.2668828,0.0009965634,0.7268916,0.0001062882,0.0001853809,0.00002180391,0.003820533,0.00001843097,0.0001271383,0.00004758707,0.00006573293,0.0008361636],"study_design_scores_gemma":[0.4421004,0.01026325,0.5332667,0.001630258,0.0008522445,0.001586757,0.008170282,0.0008428347,0.0009199728,0.00006297692,0.00006484935,0.0002394093],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976521,0.000430056,0.00005888157,0.0003399777,0.0001011435,0.001357352,0.000002723066,0.00000472108,0.00005307776],"genre_scores_gemma":[0.9996344,0.0002147989,0.00002975732,0.00005259306,0.00001021549,0.00002369154,0.000004914439,0.00001906681,0.00001052187],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1936249,"threshold_uncertainty_score":0.3174309,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01349613382425642,"score_gpt":0.3158040824774118,"score_spread":0.3023079486531554,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}