{"id":"W2008966333","doi":"10.1016/j.ijrobp.2015.04.011","title":"XRCC1 Polymorphism Associated With Late Toxicity After Radiation Therapy in Breast Cancer Patients","year":2015,"lang":"en","type":"article","venue":"International Journal of Radiation Oncology*Biology*Physics","topic":"Effects of Radiation Exposure","field":"Medicine","cited_by":69,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"Niilo Helanderin Säätiö; Institute of Cancer Research; National Institute of Radiological Sciences; Canadian Institutes of Health Research; Bundesamt für Strahlenschutz; Medical Research and Materiel Command; Deutsche Krebshilfe; National Cancer Institute; Dietmar Hopp Stiftung; National Institute for Health and Care Research; Novartis; Cancer Research UK; American Cancer Society; National Institutes of Health; Breast Cancer Campaign; California Breast Cancer Research Program; U.S. Department of Defense","keywords":"XRCC1; Oncology; Breast cancer; Medicine; Internal medicine; Radiation therapy; Toxicity; Cancer; Genotype; Biology; Genetics; Single-nucleotide polymorphism; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007473603,0.0002651058,0.0005678405,0.0003462188,0.00003732322,0.00003151232,0.0002732748,0.0003385819,0.00008562474],"category_scores_gemma":[0.000395744,0.0002159572,0.000155005,0.0003576791,0.0001378917,0.0005694192,0.00003142871,0.0005714569,0.00001944009],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00216057,"about_ca_system_score_gemma":0.001029458,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007208675,"about_ca_topic_score_gemma":0.00003106486,"domain_scores_codex":[0.9976903,0.0003846764,0.0007809924,0.00026714,0.0005801127,0.0002967486],"domain_scores_gemma":[0.9963662,0.0002843085,0.001304059,0.0001463521,0.001652209,0.0002468409],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002163078,0.001029562,0.9101378,0.00000297375,0.0005100114,0.00005966118,0.0006938814,0.0007929191,0.0005397418,0.0001595246,0.0009703991,0.08294048],"study_design_scores_gemma":[0.02003971,0.002296732,0.9713189,0.0001077776,0.00008641975,0.00007615478,0.00002496658,0.001630769,0.0008279847,0.0009628539,0.002392612,0.0002351041],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9901313,0.0006161002,0.0003279675,0.006455961,0.001678774,0.0003865301,0.000149132,0.00004136985,0.0002128843],"genre_scores_gemma":[0.9946675,0.0005304825,0.0002716455,0.002779343,0.001433095,0.00003760256,0.0001804592,0.00004417315,0.00005572075],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08270538,"threshold_uncertainty_score":0.880648,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01412481094138868,"score_gpt":0.3057843440457934,"score_spread":0.2916595331044047,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}