{"id":"W2009020908","doi":"10.1523/jneurosci.2850-06.2006","title":"A Progressive and Cell Non-Autonomous Increase in Striatal Neural Stem Cells in the Huntington's Disease R6/2 Mouse","year":2006,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Genetic Neurodegenerative Diseases","field":"Neuroscience","cited_by":52,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Dalhousie University; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Stem Cell Network","keywords":"Neurosphere; Neural stem cell; Stem cell; Progenitor cell; Biology; Adult stem cell; Subependymal zone; Neuroepithelial cell; Cell biology; Population; Subventricular zone; Endothelial stem cell; Neuroscience; In vitro; Medicine; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000221229,0.0006579885,0.0003544156,0.001334206,0.0001960426,0.0004100236,0.0002562418,0.0007628425,0.002136429],"category_scores_gemma":[0.0001399717,0.0005014875,0.0003737384,0.0002226686,0.0004048821,0.0002892891,0.0003324559,0.0009008466,0.0007569178],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002103545,"about_ca_system_score_gemma":0.0001519327,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005234041,"about_ca_topic_score_gemma":0.0008297146,"domain_scores_codex":[0.9997255,0.00002625573,0.00003719597,0.00008986461,0.00008517067,0.00003589383],"domain_scores_gemma":[0.999569,0.0000479324,0.0001313148,0.0000430615,0.00003182887,0.0001769305],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008072893,0.00003377707,0.000200132,0.00001777997,0.000004605044,0.0001634115,0.00002671713,0.00002866483,0.9987537,0.00007475731,0.00002794154,0.0005877282],"study_design_scores_gemma":[0.0001029647,0.001231807,0.02928673,0.00002951482,0.00005838859,0.003292371,0.00008115519,0.00123713,0.9608255,0.0002091544,0.003620229,0.0000250564],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9927692,0.001499732,0.002052511,0.0001232305,0.00002526384,0.00003605185,0.0009746954,0.0002775186,0.002241813],"genre_scores_gemma":[0.9664855,0.001951823,0.006976978,0.0001573075,0.00003675501,0.0001322984,0.001982135,0.0002329782,0.02204408],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002136429,"threshold_uncertainty_score":0.007147074,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0172246868882875,"score_gpt":0.2484055989723848,"score_spread":0.2311809120840974,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}