{"id":"W2009056026","doi":"10.1038/srep09460","title":"A novel PKD2L1 C-terminal domain critical for trimerization and channel function","year":2015,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Genetic and Kidney Cyst Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Alberta Innovates; Kidney Foundation of Canada","keywords":"Xenopus; Transient receptor potential channel; Chemistry; Biology; C-terminus; Cell biology; Biochemistry; Biophysics; Receptor; Gene; Amino acid","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001251382,0.0003536331,0.0002623178,0.0001528603,0.0002516434,0.0003064949,0.0003129101,0.0004455088,0.001578693],"category_scores_gemma":[0.0001671228,0.0001056806,0.0003683592,0.0001580813,0.0002198637,0.0002436558,0.0002306529,0.0004920355,0.0006135593],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005503141,"about_ca_system_score_gemma":0.0003324993,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000496368,"about_ca_topic_score_gemma":0.0005727253,"domain_scores_codex":[0.9998881,0.00001722897,0.000011856,0.00003564034,0.00002615617,0.00002121094],"domain_scores_gemma":[0.999841,0.00002504331,0.00003961239,0.00001214333,0.00001874095,0.00006355326],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001775757,0.00002083483,0.0004193429,0.00005903621,0.00000480801,0.0002856916,0.00001535104,0.0001079591,0.9978322,0.00009254683,0.00007493127,0.000909703],"study_design_scores_gemma":[0.00006768189,0.0001420683,0.01276104,0.00001282616,0.00002107696,0.002198464,0.00003429487,0.003198331,0.9762399,0.00008116918,0.005226195,0.00001683966],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9918461,0.001350521,0.004805938,0.0001692771,0.00004404002,0.00004797452,0.000587642,0.00008714022,0.001061318],"genre_scores_gemma":[0.9915588,0.0002908502,0.004496009,0.0001672923,0.00001693486,0.00004986868,0.001679863,0.0000219931,0.001718404],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001578693,"threshold_uncertainty_score":0.00528121,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02158614572052713,"score_gpt":0.2754642719245477,"score_spread":0.2538781262040206,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}