{"id":"W2009066388","doi":"10.2174/156652308785160674","title":"CCR5 as Target for HIV-1 Gene Therapy","year":2008,"lang":"en","type":"review","venue":"Current Gene Therapy","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Chemokine receptor; Chemokine receptor CCR5; Biology; CXCR4; Chemokine; C-C chemokine receptor type 6; Immune system; Virology; CCR1; Receptor; Immunology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002051549,0.0002721813,0.0002767575,0.0002422941,0.0001060578,0.0004087162,0.0003210745,0.0004410729,0.001586011],"category_scores_gemma":[0.0001286501,0.00007998313,0.0002517209,0.0001794178,0.0001643788,0.0001900767,0.0001982638,0.0006445837,0.0005097939],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004767358,"about_ca_system_score_gemma":0.0002428934,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005591987,"about_ca_topic_score_gemma":0.000729706,"domain_scores_codex":[0.9998902,0.00002174456,0.000005875681,0.00002161024,0.00003420922,0.00002638773],"domain_scores_gemma":[0.9999684,0.000005596198,0.000008118725,0.000003644163,0.00000744511,0.000006876486],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004047597,0.0002526834,0.0005375974,0.001155886,0.00005713072,0.0003338055,0.0000893141,0.001413496,0.8452367,0.01065401,0.00459073,0.1352739],"study_design_scores_gemma":[0.0002273163,0.002941833,0.002083694,0.0002381966,0.0002263821,0.001622589,0.00003996057,0.005003633,0.7134323,0.00108925,0.2730564,0.00003843293],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.4430715,0.4099815,0.08257723,0.003793157,0.001985021,0.001008656,0.001332561,0.0009066746,0.05534352],"genre_scores_gemma":[0.8900214,0.06858683,0.02137935,0.001352035,0.0001706443,0.0004253016,0.001068189,0.00005839179,0.01693782],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.001586011,"threshold_uncertainty_score":0.005305767,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1116089137515411,"score_gpt":0.3891599429324618,"score_spread":0.2775510291809207,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}