{"id":"W2009341575","doi":"10.1016/s1773-2247(09)50008-1","title":"Formulation of glycerolipidic prodrugs into PEGylated liposomes for brain delivery","year":2009,"lang":"en","type":"article","venue":"Journal of Drug Delivery Science and Technology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"National Research Council Canada; Institute for Biological Sciences","funders":"","keywords":"Liposome; Prodrug; Drug delivery; Pharmacology; Nanotechnology; Materials science; Biomedical engineering; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001778279,0.0003119688,0.0001680043,0.0001698088,0.0001042739,0.000240691,0.0002690656,0.0002900367,0.0009813653],"category_scores_gemma":[0.0001548627,0.0001404782,0.0001844362,0.00009747669,0.0001304329,0.0003636182,0.000282853,0.0004662533,0.0003972055],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003783015,"about_ca_system_score_gemma":0.0002777372,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009899522,"about_ca_topic_score_gemma":0.0008110699,"domain_scores_codex":[0.9999512,0.000006582648,0.000004662662,0.00001000142,0.000008170641,0.00001927352],"domain_scores_gemma":[0.9999645,0.000006387938,0.0000109174,0.000003877467,0.000006529933,0.000007696819],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002327089,0.00004126023,0.0000610986,0.00006893394,0.00001110314,0.00006950952,0.00003377688,0.0006572296,0.9908585,0.0004746179,0.00015771,0.007333635],"study_design_scores_gemma":[0.00004550177,0.0002208705,0.000165393,0.000006198235,0.00001822572,0.0000648947,0.000008905292,0.001061564,0.996365,0.00006609112,0.001971575,0.00000583382],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9723368,0.001911927,0.02187748,0.0002969173,0.00008015463,0.0003540076,0.0004989369,0.0002603061,0.002383536],"genre_scores_gemma":[0.9888232,0.0008461748,0.007659816,0.00005166577,0.000008741462,0.00009216739,0.000241828,0.00003583486,0.002240569],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009899522,"threshold_uncertainty_score":0.003282964,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007362735684372616,"score_gpt":0.2572069219320128,"score_spread":0.2498441862476402,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}