{"id":"W2009420762","doi":"10.1038/onc.2010.43","title":"Transcription factor regulatory networks in mammary epithelial development and tumorigenesis","year":2010,"lang":"en","type":"review","venue":"Oncogene","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":46,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University Health Centre","funders":"National Cancer Institute; Terry Fox Foundation; Canada Research Chairs","keywords":"Myoepithelial cell; Biology; Transcription factor; Progenitor cell; Mammary gland; Carcinogenesis; Cell biology; Cell fate determination; Cellular differentiation; Stem cell; Immunology; Breast cancer; Genetics; Cancer; Gene; Immunohistochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002531373,0.000375002,0.001457497,0.0002294649,0.0000434547,0.00001930672,0.0001000444,0.0004327264,0.0000947384],"category_scores_gemma":[0.000008661237,0.0003040624,0.0002502697,0.000219573,0.00003960375,0.00004183271,0.00003652791,0.0004630073,0.0000132666],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002439947,"about_ca_system_score_gemma":0.0007891293,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002677453,"about_ca_topic_score_gemma":0.0001555613,"domain_scores_codex":[0.9983585,0.00006163806,0.0005965747,0.0004642197,0.0002179537,0.0003010725],"domain_scores_gemma":[0.9992179,0.00003012902,0.0001627881,0.0003496409,0.00003134929,0.0002082191],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001853768,0.00005416732,0.00001140418,0.004158482,0.00007600442,0.00007827985,0.00005634389,1.75495e-7,0.0002559364,0.000009648669,0.00005331418,0.9952277],"study_design_scores_gemma":[0.0005148812,0.00003987614,0.0002165623,0.003596662,0.000451017,0.0001338082,0.000003589189,0.000001834392,0.0003402676,0.000001713087,0.9944118,0.0002880096],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001538997,0.9963837,0.0002433539,0.00002010619,0.0007532294,0.0007154892,0.00003299776,0.00003042997,0.0002817566],"genre_scores_gemma":[0.0001062883,0.9950587,0.002832575,0.00006009226,0.0005709747,0.0001179474,0.0001563703,0.00006485802,0.00103221],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9949397,"threshold_uncertainty_score":0.9999412,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04564023024912162,"score_gpt":0.3056954835501793,"score_spread":0.2600552533010577,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}