{"id":"W2009462371","doi":"10.1002/art.33377","title":"The autoantigen DNA topoisomerase I interacts with chemokine receptor 7 and exerts cytokine‐like effects on dermal fibroblasts","year":2011,"lang":"en","type":"article","venue":"Arthritis & Rheumatism","topic":"Systemic Sclerosis and Related Diseases","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier de l’Université de Montréal; Université de Montréal; Hôpital Notre-Dame","funders":"Canadian Institutes of Health Research; Université de Montréal","keywords":"Fibroblast; Chemokine receptor; Cell biology; C-C chemokine receptor type 6; Chemokine; Biology; C-C chemokine receptor type 7; Receptor; Molecular biology; MAPK/ERK pathway; Signal transduction; Chemistry; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000191206,0.0006583974,0.000204486,0.0002709171,0.0001819716,0.0002940155,0.0001352178,0.0002364102,0.00165316],"category_scores_gemma":[0.0001705573,0.0001551821,0.0004164091,0.0001126333,0.0001654315,0.0001674741,0.0002054544,0.0003265341,0.0005636233],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000244539,"about_ca_system_score_gemma":0.0001448366,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006072005,"about_ca_topic_score_gemma":0.000641886,"domain_scores_codex":[0.9996693,0.00008140113,0.00001828317,0.00005011875,0.00007772255,0.000103288],"domain_scores_gemma":[0.9998848,0.00002766253,0.00003093209,0.00001242993,0.00001365303,0.00003032108],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004364768,0.00001858603,0.0003110977,0.00003922596,0.000005151895,0.0001222043,0.000007801053,0.00002146609,0.9987131,0.00001480809,0.000023675,0.0006792351],"study_design_scores_gemma":[0.00002738003,0.001141684,0.02122724,0.00001813575,0.00003740012,0.001151945,0.0000966744,0.0007438656,0.9731852,0.00002891717,0.002334071,0.000007500189],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9898559,0.005104054,0.001647849,0.00008112961,0.00005646313,0.00004095486,0.0001659993,0.00004896166,0.002998559],"genre_scores_gemma":[0.9956452,0.001708275,0.0008315189,0.00004365634,0.00003308585,0.00003919234,0.0001474121,0.000005448943,0.001546231],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00165316,"threshold_uncertainty_score":0.005530357,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00881657470102268,"score_gpt":0.2008598658825927,"score_spread":0.19204329118157,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}