{"id":"W2009462371","doi":"10.1002/art.33377","title":"The autoantigen DNA topoisomerase I interacts with chemokine receptor 7 and exerts cytokine‐like effects on dermal fibroblasts","year":2011,"lang":"en","type":"article","venue":"Arthritis & Rheumatism","topic":"Systemic Sclerosis and Related Diseases","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier de l’Université de Montréal; Université de Montréal; Hôpital Notre-Dame","funders":"Canadian Institutes of Health Research; Université de Montréal","keywords":"Fibroblast; Chemokine receptor; Cell biology; C-C chemokine receptor type 6; Chemokine; Biology; C-C chemokine receptor type 7; Receptor; Molecular biology; MAPK/ERK pathway; Signal transduction; Chemistry; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001648906,0.0002850863,0.0004004682,0.00008147774,0.0002821873,0.00006526721,0.0001078772,0.000117821,0.0002124197],"category_scores_gemma":[0.000118955,0.0001721274,0.00008298588,0.0001415524,0.0001596306,0.000158719,0.00005696584,0.0002119757,0.0001294356],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003720962,"about_ca_system_score_gemma":0.00005991296,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001296114,"about_ca_topic_score_gemma":0.00005018473,"domain_scores_codex":[0.9983923,0.00008528175,0.0003753733,0.0003816509,0.0003289107,0.0004364148],"domain_scores_gemma":[0.9987275,0.0002837688,0.0001540314,0.0004237177,0.00007352342,0.0003374657],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.001461522,0.0004790818,0.01257178,0.0003780893,0.0005823778,0.0003814283,0.00513083,0.000001434891,0.02078554,0.0007003417,0.03038757,0.92714],"study_design_scores_gemma":[0.01947027,0.005039547,0.6645708,0.08575486,0.0002760699,0.002586404,0.001049391,0.0001631121,0.2112342,0.0002388073,0.008390923,0.00122561],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.984688,0.01143483,0.00001452567,0.0005733914,0.0004574718,0.0006812427,0.00001457563,0.0001325918,0.002003308],"genre_scores_gemma":[0.9882655,0.01027549,0.0002987677,0.0005232799,0.00008388281,0.00008929663,0.00003487152,0.00004917545,0.000379711],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9259144,"threshold_uncertainty_score":0.7019154,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00881657470102268,"score_gpt":0.2008598658825927,"score_spread":0.19204329118157,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}