{"id":"W2009504090","doi":"10.1101/gad.232215.113","title":"Context dependency of Set1/COMPASS-mediated histone H3 Lys4 trimethylation","year":2014,"lang":"en","type":"article","venue":"Genes & Development","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":54,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Biology; Histone H3; Chromatin immunoprecipitation; H3K4me3; Histone; Genetics; Context (archaeology); Chromatin; Histone H2B; Histone methyltransferase; Homeotic gene; Cell biology; Mutant; Gene; Promoter; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002524407,0.0001478081,0.00018389,0.00004934668,0.00006354995,0.000008857964,0.0001732295,0.0001231557,0.00003034856],"category_scores_gemma":[0.00003990288,0.0001482828,0.00005505611,0.00006332889,0.00003452002,0.000002067598,0.00009576701,0.00004211124,0.00003055073],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003862575,"about_ca_system_score_gemma":0.000176609,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001915386,"about_ca_topic_score_gemma":0.00008758621,"domain_scores_codex":[0.9989986,0.0000450368,0.0003668035,0.0002552586,0.0001446198,0.0001897136],"domain_scores_gemma":[0.999386,0.00001426799,0.0001678565,0.0002507953,0.0001142736,0.00006681292],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003979974,0.00008224564,0.005373475,0.00003999416,0.00009253282,6.349358e-7,0.0002424089,0.0001739539,0.8636653,0.0001389188,0.0004788917,0.1296719],"study_design_scores_gemma":[0.001040082,0.0001444676,0.037898,0.00001612272,0.00002257911,0.000007316681,0.0001050964,0.0008003053,0.8223368,0.0001815108,0.1370775,0.0003702411],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9892194,0.001063242,0.008503775,0.00005197557,0.0002001571,0.0001383228,0.000008711358,0.00001087128,0.0008035497],"genre_scores_gemma":[0.9895143,0.0001529733,0.00927176,0.0001041354,0.00006444646,0.00001766794,0.0004333491,0.00001959553,0.0004217535],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1365986,"threshold_uncertainty_score":0.6046798,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007178477673275646,"score_gpt":0.2285239675370522,"score_spread":0.2213454898637766,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}