{"id":"W2009504090","doi":"10.1101/gad.232215.113","title":"Context dependency of Set1/COMPASS-mediated histone H3 Lys4 trimethylation","year":2014,"lang":"en","type":"article","venue":"Genes & Development","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":54,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Biology; Histone H3; Chromatin immunoprecipitation; H3K4me3; Histone; Genetics; Context (archaeology); Chromatin; Histone H2B; Histone methyltransferase; Homeotic gene; Cell biology; Mutant; Gene; Promoter; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009364591,0.0004030118,0.0003049998,0.0001852975,0.0002145606,0.0004069698,0.0003541098,0.000223196,0.003186545],"category_scores_gemma":[0.0001597556,0.0002645366,0.000324319,0.0001369693,0.0002726018,0.00022145,0.0007510838,0.0006528237,0.0007061327],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004145376,"about_ca_system_score_gemma":0.0001969195,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001550682,"about_ca_topic_score_gemma":0.003187831,"domain_scores_codex":[0.999808,0.00001469302,0.00001555423,0.0000576028,0.00006687702,0.00003718357],"domain_scores_gemma":[0.9998386,0.00002765869,0.00003557847,0.0000208371,0.00002014911,0.00005708644],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005569811,0.000008437852,0.0002875016,0.0000299986,0.000004436351,0.00004274304,0.000007233856,0.00004604765,0.9989672,0.00003020273,0.00002529332,0.0004952339],"study_design_scores_gemma":[0.000004095811,0.00004966712,0.01430184,0.000003517863,0.000008359494,0.0001344325,0.00002201948,0.0006005657,0.9836897,0.00002240512,0.001156006,0.000007354055],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941337,0.001127149,0.001357294,0.00006989908,0.00003312948,0.00001699461,0.001036673,0.0001269065,0.002098265],"genre_scores_gemma":[0.9952241,0.0003439338,0.001010229,0.00005406409,0.000004959116,0.00001407617,0.001280883,0.00004671598,0.002021159],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003186545,"threshold_uncertainty_score":0.01066011,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007178477673275646,"score_gpt":0.2285239675370522,"score_spread":0.2213454898637766,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}