{"id":"W2009515210","doi":"10.1016/j.semcancer.2006.10.007","title":"Formation of non-random extrachromosomal elements during development, differentiation and oncogenesis","year":2006,"lang":"en","type":"review","venue":"Seminars in Cancer Biology","topic":"Chromosomal and Genetic Variations","field":"Agricultural and Biological Sciences","cited_by":84,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Manitoba; CancerCare Manitoba","funders":"National Cancer Institute; Canadian Institutes of Health Research","keywords":"Extrachromosomal DNA; Chromatin; Biology; Telomere; Genome; Genetics; Gene; Minichromosome; Carcinogenesis; DNA; Computational biology; Cell biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004199602,0.0006537495,0.001133721,0.0008222261,0.0001981674,0.0006842065,0.001038936,0.0009094576,0.00119948],"category_scores_gemma":[0.0003876479,0.0002490247,0.0002630271,0.001210745,0.0006129569,0.000928644,0.0004940802,0.0007433479,0.001400326],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004438533,"about_ca_system_score_gemma":0.0004085386,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003290962,"about_ca_topic_score_gemma":0.0005119687,"domain_scores_codex":[0.9998311,0.00002001375,0.00001958271,0.0000471242,0.00006172741,0.00002042385],"domain_scores_gemma":[0.9998216,0.00009051242,0.00003006655,0.00001488439,0.00003104968,0.00001193813],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001435322,0.00004055746,0.0004928928,0.00565556,0.00004549091,0.0009335559,0.0001128703,0.0007602187,0.05502009,0.006186629,0.003757038,0.9268517],"study_design_scores_gemma":[0.00003757681,0.0002601608,0.003550754,0.0009092288,0.0001674865,0.007838659,0.0002308894,0.0002501028,0.06908958,0.005056084,0.9125704,0.00003915778],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002879395,0.9918358,0.002517762,0.0001283807,0.0003175717,0.00001076865,0.00003085895,0.00003149449,0.002248025],"genre_scores_gemma":[0.01022317,0.9856442,0.001225814,0.0001026334,0.0001824014,0.00001874283,0.00008551533,0.000007219104,0.002510268],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00119948,"threshold_uncertainty_score":0.004012644,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03076137857868989,"score_gpt":0.3027810089263616,"score_spread":0.2720196303476717,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}