{"id":"W2009570513","doi":"10.1016/j.bbamem.2006.11.014","title":"Coencapsulation of irinotecan and floxuridine into low cholesterol-containing liposomes that coordinate drug release in vivo","year":2006,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Biomembranes","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":133,"is_retracted":false,"has_abstract":false,"ca_institutions":"BC Cancer Agency; Celator Pharmaceuticals (Canada)","funders":"","keywords":"Floxuridine; Irinotecan; Triethanolamine; Chemistry; Liposome; Chromatography; In vivo; Pharmacology; Drug; Chemotherapy; Biochemistry; Internal medicine; Analytical Chemistry (journal); Fluorouracil; Medicine; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002423874,0.0002974992,0.0002849977,0.0002007578,0.0001516802,0.0002570667,0.0002334557,0.0002960714,0.000597531],"category_scores_gemma":[0.0001741276,0.0001301707,0.0002018096,0.0001671061,0.000249539,0.0003782733,0.000154357,0.000461735,0.0001821568],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006452488,"about_ca_system_score_gemma":0.0003353399,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001414978,"about_ca_topic_score_gemma":0.001904611,"domain_scores_codex":[0.9998914,0.00001314941,0.00001181747,0.00002610002,0.00002354118,0.00003401274],"domain_scores_gemma":[0.9998894,0.0000261232,0.00002765245,0.00001859547,0.00001289761,0.00002538475],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002585733,0.00003302389,0.00006073757,0.00002204824,0.000007408374,0.00002623112,0.00001817462,0.0001140326,0.9984706,0.0001143168,0.00002928552,0.0008456607],"study_design_scores_gemma":[0.00001701069,0.0001486777,0.0003386683,0.000001205483,0.000008701998,0.00002628546,0.000004386846,0.000348813,0.9987388,0.000007959187,0.0003578142,0.000001650152],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964066,0.0007570283,0.001548242,0.0000583331,0.00003032036,0.00003984161,0.0001336481,0.0000546895,0.0009712616],"genre_scores_gemma":[0.9959674,0.0003924597,0.001794931,0.00002188872,0.000008891286,0.00003696409,0.00017428,0.0000188191,0.001584349],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001414978,"threshold_uncertainty_score":0.004681647,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006989409436993677,"score_gpt":0.2187778527666973,"score_spread":0.2117884433297036,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}