{"id":"W2009604336","doi":"10.1042/bj20140145","title":"Inhibition of histone binding by supramolecular hosts","year":2014,"lang":"en","type":"article","venue":"Biochemical Journal","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria","funders":"National Institute of Environmental Health Sciences; National Institute of General Medical Sciences; Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Cancer Institute; National Institutes of Health","keywords":"Chromodomain; Histone H3; Heterochromatin protein 1; PHD finger; Nucleosome; Cell biology; Bromodomain; EZH2; Biology; Histone; Chromatin; Histone code; Histone methylation; Epigenetics; Chromatin remodeling; Chemistry; Biochemistry; DNA methylation; Heterochromatin; DNA; Transcription factor; Gene expression; Helicase; Zinc finger; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009102798,0.0002646778,0.0001669486,0.0001143538,0.0001033686,0.0002234615,0.0002608287,0.0002256604,0.0009945125],"category_scores_gemma":[0.0001761894,0.0001039892,0.000121921,0.0001101701,0.000191869,0.0001560215,0.0002530529,0.000271589,0.0001440741],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000249043,"about_ca_system_score_gemma":0.0001254598,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002962287,"about_ca_topic_score_gemma":0.0003989732,"domain_scores_codex":[0.9998986,0.00001246631,0.000005731677,0.00002600269,0.00002979217,0.00002748942],"domain_scores_gemma":[0.9998928,0.00003854022,0.0000309799,0.00001185798,0.000008886663,0.00001684483],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007664056,0.00001891066,0.00004251698,0.00004067039,0.000005955601,0.0000248239,0.000008838937,0.0002292005,0.9981641,0.0002538029,0.00002560369,0.001108942],"study_design_scores_gemma":[0.00001150289,0.0001910505,0.0001926374,0.000001551821,0.000003842772,0.00002061911,0.000004899191,0.0008752752,0.9979423,0.00002593109,0.000727504,0.00000287022],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941011,0.0007353714,0.002982159,0.00004475921,0.00003202318,0.00003182247,0.00006036051,0.0000788008,0.001933508],"genre_scores_gemma":[0.9978971,0.0003051029,0.000977415,0.00002816746,0.000007331857,0.00002193887,0.00004913993,0.000008496899,0.0007052354],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009945125,"threshold_uncertainty_score":0.003326952,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003640747181218281,"score_gpt":0.2340656807674744,"score_spread":0.2304249335862561,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}