{"id":"W2009604336","doi":"10.1042/bj20140145","title":"Inhibition of histone binding by supramolecular hosts","year":2014,"lang":"en","type":"article","venue":"Biochemical Journal","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria","funders":"National Institute of Environmental Health Sciences; National Institute of General Medical Sciences; Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Cancer Institute; National Institutes of Health","keywords":"Chromodomain; Histone H3; Heterochromatin protein 1; PHD finger; Nucleosome; Cell biology; Bromodomain; EZH2; Biology; Histone; Chromatin; Histone code; Histone methylation; Epigenetics; Chromatin remodeling; Chemistry; Biochemistry; DNA methylation; Heterochromatin; DNA; Transcription factor; Gene expression; Helicase; Zinc finger; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002012747,0.000111055,0.0001282815,0.00003359079,0.00005324602,0.00001985808,0.0001318331,0.0001504309,0.00001781023],"category_scores_gemma":[0.00009251299,0.0001078962,0.0001078625,0.00004960229,0.00007438853,0.000002217621,0.00006709136,0.0001219657,0.000005051691],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002493364,"about_ca_system_score_gemma":0.00003268295,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002001292,"about_ca_topic_score_gemma":2.743633e-7,"domain_scores_codex":[0.9992157,0.00003721975,0.000262845,0.000162142,0.0001400243,0.0001821288],"domain_scores_gemma":[0.9994688,0.000006527644,0.0001654285,0.0001633943,0.00008084862,0.0001150266],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002029909,0.00004977105,0.0002277973,0.000010708,0.00002030413,0.000001076247,0.000009302109,0.000005089959,0.9886293,0.00004007273,0.01041676,0.000569454],"study_design_scores_gemma":[0.0004703736,0.0001730576,0.00008618357,0.00002091377,0.00001398278,0.00009495326,0.00001571533,0.000120912,0.99146,0.0001418064,0.007266576,0.000135503],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9918156,0.0005089104,0.006980165,0.00009583819,0.0001033499,0.00003898805,0.00001704748,0.000003940672,0.0004361429],"genre_scores_gemma":[0.9974666,0.0001202744,0.001852982,0.0001095826,0.0001851781,0.000001438368,0.0001419736,0.00001835045,0.0001036654],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005650938,"threshold_uncertainty_score":0.4399881,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003640747181218281,"score_gpt":0.2340656807674744,"score_spread":0.2304249335862561,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}