{"id":"W2009633046","doi":"10.1016/j.fgb.2009.06.008","title":"The Candida albicans histidine kinase Chk1p: Signaling and cell wall mannan","year":2009,"lang":"en","type":"article","venue":"Fungal Genetics and Biology","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":42,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Guelph","funders":"National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; U.S. Public Health Service; National Institutes of Health","keywords":"Mannan; Mutant; Biology; Candida albicans; Histidine; Kinase; Histidine kinase; Biochemistry; Saccharomyces cerevisiae; Biophysics; Molecular biology; Cell biology; Yeast; Amino acid; Microbiology; Gene; Polysaccharide","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001862634,0.000123422,0.0001940156,0.00002246882,0.0001893953,0.00001779971,0.00005530402,0.0001036693,0.00002935767],"category_scores_gemma":[0.00003384237,0.00007522806,0.00003664968,0.00005155464,0.0001924932,0.000007627993,0.00002749025,0.0001367658,0.000002833751],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001577174,"about_ca_system_score_gemma":0.00004289738,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004733785,"about_ca_topic_score_gemma":0.0001197881,"domain_scores_codex":[0.9992027,0.00003950898,0.0001775136,0.0002580764,0.00005412692,0.0002680177],"domain_scores_gemma":[0.9995084,0.00007515105,0.00004306191,0.0001826837,0.00005318521,0.000137481],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0005591556,0.0001272866,0.3927216,0.00006203243,0.00003693203,0.0000453617,0.0002310567,0.000001454951,0.5450549,0.001710911,0.001432126,0.05801724],"study_design_scores_gemma":[0.001588506,0.003344284,0.8354677,0.00004247002,0.0001459576,0.00005653274,0.0002191567,0.000541807,0.02121748,0.002963582,0.1340764,0.0003361724],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9821236,0.01418068,0.00005703024,0.001956547,0.00006689465,0.0001550083,0.00001368103,0.00001336518,0.001433258],"genre_scores_gemma":[0.9936928,0.003591535,0.0002416894,0.0008710636,0.0001278244,0.000003342776,0.0000143486,0.000006011287,0.001451444],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5238373,"threshold_uncertainty_score":0.3067711,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02013377872590595,"score_gpt":0.2752655835047519,"score_spread":0.2551318047788459,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}