{"id":"W2009633046","doi":"10.1016/j.fgb.2009.06.008","title":"The Candida albicans histidine kinase Chk1p: Signaling and cell wall mannan","year":2009,"lang":"en","type":"article","venue":"Fungal Genetics and Biology","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":42,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Guelph","funders":"National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; U.S. Public Health Service; National Institutes of Health","keywords":"Mannan; Mutant; Biology; Candida albicans; Histidine; Kinase; Histidine kinase; Biochemistry; Saccharomyces cerevisiae; Biophysics; Molecular biology; Cell biology; Yeast; Amino acid; Microbiology; Gene; Polysaccharide","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001446344,0.0006789937,0.0002179281,0.0003002394,0.0004017487,0.0008062545,0.0003695109,0.0005218342,0.001452716],"category_scores_gemma":[0.0001839727,0.0002656866,0.0001942059,0.0002188057,0.0003158588,0.0004764632,0.0005907892,0.0007502883,0.0008225428],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009951427,"about_ca_system_score_gemma":0.0004253667,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001058161,"about_ca_topic_score_gemma":0.0008267289,"domain_scores_codex":[0.9998859,0.00001161204,0.000006200464,0.00002305255,0.00003247361,0.00004078627],"domain_scores_gemma":[0.9999088,0.00001152295,0.00002308857,0.000008378657,0.00001260539,0.00003547113],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004043118,0.00001821145,0.0003352732,0.00007350141,0.000006152102,0.0003016752,0.0000121835,0.0003069012,0.991845,0.0009569065,0.0005883002,0.005151704],"study_design_scores_gemma":[0.00002334172,0.0000708788,0.005922536,0.0000110253,0.00001611286,0.00100419,0.00005920593,0.002428025,0.9844868,0.0006121322,0.005350019,0.00001575704],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9682751,0.01236776,0.008019561,0.002307758,0.0002317315,0.00004845991,0.00146281,0.0004127703,0.006873911],"genre_scores_gemma":[0.9905769,0.002461366,0.001562678,0.000123338,0.0000268816,0.00001472684,0.0005814718,0.00002670126,0.004625881],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001452716,"threshold_uncertainty_score":0.007220328,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02013377872590595,"score_gpt":0.2752655835047519,"score_spread":0.2551318047788459,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}