{"id":"W2009636791","doi":"10.1371/journal.pone.0027478","title":"A Role for the Ubiquitin Ligase Nedd4 in Membrane Sorting of LAPTM4 Proteins","year":2011,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto; SickKids Foundation","funders":"Canadian Institutes of Health Research; Medical Center, University of Rochester","keywords":"NEDD4; Ubiquitin ligase; Ubiquitin; Ubiquitin-Protein Ligases; Cell biology; Sorting; Chemistry; Membrane protein; Biology; Biochemistry; Membrane; Computer science; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001820176,0.00006417588,0.0001022424,0.00001923374,0.0000291573,0.000002806716,0.0001002603,0.00006735748,0.000036075],"category_scores_gemma":[0.00005133272,0.00005190524,0.00005486159,0.00004170848,0.00003224423,0.000001844925,0.00001676132,0.00004531257,0.000001217132],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000002442578,"about_ca_system_score_gemma":0.00002691819,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001008365,"about_ca_topic_score_gemma":0.0003236854,"domain_scores_codex":[0.999481,0.00001318018,0.0001728856,0.0001323239,0.00007316694,0.000127452],"domain_scores_gemma":[0.9996848,0.000007387166,0.00006602867,0.000173674,0.00004121631,0.00002692446],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001658602,0.0003517947,0.00232034,0.00009354121,0.00006016329,6.191703e-7,0.0003739445,0.000004296478,0.9962725,0.0001234949,9.50434e-7,0.0002325121],"study_design_scores_gemma":[0.0003955048,0.0001799905,0.001282589,0.00003547213,0.00005721312,4.247912e-7,0.00012928,0.0003548232,0.9970312,0.0001329998,0.0003339109,0.00006658831],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960886,0.0005642567,0.002104881,0.00007445409,0.000007861612,0.0005190331,0.00001274995,0.000005590593,0.0006225982],"genre_scores_gemma":[0.9979814,0.00007543747,0.001313089,0.00004928283,0.00006333338,0.0001064804,0.0001826987,0.00001219715,0.0002160904],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001892816,"threshold_uncertainty_score":0.2116634,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03738038222917676,"score_gpt":0.2109926913790837,"score_spread":0.1736123091499069,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}